IRF9

Interferon regulatory factor 9 is a protein that in humans is encoded by the IRF9 gene, previously known as ISGF3G.[5][6][7]

IRF9
Identifiers
AliasesIRF9, IRF-9, ISGF3, ISGF3G, p48, interferon regulatory factor 9
External IDsOMIM: 147574 MGI: 107587 HomoloGene: 4436 GeneCards: IRF9
Orthologs
SpeciesHumanMouse
Entrez

10379

16391

Ensembl

ENSG00000213928
ENSG00000285048

ENSMUSG00000002325

UniProt

Q00978

Q61179

RefSeq (mRNA)

NM_006084
NM_001385400
NM_001385401
NM_001385402

NM_001159417
NM_001159418
NM_008394

RefSeq (protein)

NP_006075

NP_001152889
NP_001152890
NP_032420

Location (UCSC)Chr 14: 24.16 – 24.17 MbChr 14: 55.84 – 55.85 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

IRF9 has been shown to interact with STAT2[8][9] and STAT1.[8]

References

  1. ENSG00000285048 GRCh38: Ensembl release 89: ENSG00000213928, ENSG00000285048 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000002325 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Veals SA, Schindler C, Leonard D, Fu XY, Aebersold R, Darnell JE Jr, Levy DE (Aug 1992). "Subunit of an alpha-interferon-responsive transcription factor is related to interferon regulatory factor and Myb families of DNA-binding proteins". Mol Cell Biol. 12 (8): 3315–24. doi:10.1128/MCB.12.8.3315. PMC 364572. PMID 1630447.
  6. McCusker D, Wilson M, Trowsdale J (Jun 1999). "Organization of the genes encoding the human proteasome activators PA28alpha and beta". Immunogenetics. 49 (5): 438–45. doi:10.1007/s002510050517. PMID 10199920. S2CID 40575791.
  7. "Entrez Gene: ISGF3G interferon-stimulated transcription factor 3, gamma 48kDa".
  8. Horvath, C M; Stark G R; Kerr I M; Darnell J E (Dec 1996). "Interactions between STAT and non-STAT proteins in the interferon-stimulated gene factor 3 transcription complex". Mol. Cell. Biol. UNITED STATES. 16 (12): 6957–64. doi:10.1128/mcb.16.12.6957. ISSN 0270-7306. PMC 231699. PMID 8943351.
  9. Martinez-Moczygemba, M; Gutch M J; French D L; Reich N C (Aug 1997). "Distinct STAT structure promotes interaction of STAT2 with the p48 subunit of the interferon-alpha-stimulated transcription factor ISGF3". J. Biol. Chem. UNITED STATES. 272 (32): 20070–6. doi:10.1074/jbc.272.32.20070. ISSN 0021-9258. PMID 9242679.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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