DBP (gene)

D site of albumin promoter (albumin D-box) binding protein, also known as DBP, is a protein which in humans is encoded by the DBP gene.[5][6]

DBP
Identifiers
AliasesDBP, DABP, D-box binding PAR bZIP transcription factor, taxREB302
External IDsOMIM: 124097 MGI: 94866 HomoloGene: 1035 GeneCards: DBP
Orthologs
SpeciesHumanMouse
Entrez

1628

13170

Ensembl

ENSG00000105516

ENSMUSG00000059824

UniProt

Q10586

Q60925

RefSeq (mRNA)

NM_001352

NM_016974

RefSeq (protein)

NP_001343

NP_058670

Location (UCSC)Chr 19: 48.63 – 48.64 MbChr 7: 45.35 – 45.36 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

DBP is a member of the PAR bZIP (Proline and Acidic amino acid-Rich basic leucine ZIPper) transcription factor family.[5][7] DBP binds to an upstream promoter in the insulin gene.[8]

References

  1. GRCh38: Ensembl release 89: ENSG00000105516 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000059824 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: DBP D site of albumin promoter (albumin D-box) binding protein".
  6. Szpirer C, Riviere M, Cortese R, Nakamura T, Islam MQ, Levan G, Szpirer J (Jun 1992). "Chromosomal localization in man and rat of the genes encoding the liver-enriched transcription factors C/EBP, DBP, and HNF1/LFB-1 (CEBP, DBP, and transcription factor 1, TCF1, respectively) and of the hepatocyte growth factor/scatter factor gene (HGF)". Genomics. 13 (2): 293–300. doi:10.1016/0888-7543(92)90245-N. PMID 1535333.
  7. Khatib ZA, Inaba T, Valentine M, Look AT (Sep 1994). "Chromosomal localization and cDNA cloning of the human DBP and TEF genes". Genomics. 23 (2): 344–51. doi:10.1006/geno.1994.1510. PMID 7835883.
  8. Melloul D, Marshak S, Cerasi E (Mar 2002). "Regulation of insulin gene transcription". Diabetologia. 45 (3): 309–26. doi:10.1007/s00125-001-0728-y. PMID 11914736.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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