PNU-91356A

PNU-91356A
Clinical data
ATC code	none;
Identifiers
	IUPAC name (10R)-10-(propylamino)-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-2-one;
CAS Number	152886-85-6 ;
PubChem CID	132955;
UNII	K5FQ4JYU8H;
CompTox Dashboard (EPA)	DTXSID60934630 ;
Chemical and physical data
Formula	C13H17N3O
Molar mass	231.299 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCCNC1CC2=C3C(=CC=C2)NC(=O)N3C1;
	InChI InChI=1S/C13H17N3O/c1-2-6-14-10-7-9-4-3-5-11-12(9)16(8-10)13(17)15-11/h3-5,10,14H,2,6-8H2,1H3,(H,15,17)/t10-/m1/s1; Key:XTWUNLMHXDDOMD-SNVBAGLBSA-N;

PNU-91356A (U-91356) is a drug used in scientific research which acts as a potent and reasonably selective agonist of the dopamine receptor D₂, with lower affinity for the related D₃ and D₄ subtypes and the 5-HT_1A receptor.[1][2]

References

Moon MW, Morris JK, Heier RF, Hsi RS, Manis MO, Royer ME, et al. (1993). "Medicinal chemistry of imidazoquinolinone dopamine receptor agonists". Drug Design and Discovery. 9 (3–4): 313–22. PMID 8104520.
Piercey MF, Moon MW, Sethy VH, Schreur PJ, Smith MW, Tang AH, Von Voigtlander PF (December 1996). "Pharmacology of U-91356A, an agonist for the dopamine D2 receptor subtype". European Journal of Pharmacology. 317 (1): 29–38. doi:10.1016/s0014-2999(96)00695-4. PMID 8982716.

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[1] Moon MW, Morris JK, Heier RF, Hsi RS, Manis MO, Royer ME, et al. (1993). "Medicinal chemistry of imidazoquinolinone dopamine receptor agonists". Drug Design and Discovery. 9 (3–4): 313–22. PMID 8104520.

[2] Piercey MF, Moon MW, Sethy VH, Schreur PJ, Smith MW, Tang AH, Von Voigtlander PF (December 1996). "Pharmacology of U-91356A, an agonist for the dopamine D2 receptor subtype". European Journal of Pharmacology. 317 (1): 29–38. doi:10.1016/s0014-2999(96)00695-4. PMID 8982716.