Testosterone undecylenate
Testosterone undecylenate (TUe) is an androgen/anabolic steroid medication and androgen ester which is no longer marketed.[1][2][3] It was a component of Durasteron and Triolandren, long-acting mixtures of testosterone esters in oil solution that were administered by intramuscular injection.[4][5][6][7]
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Trade names | Durasteron, Triolandren (mixtures) |
Other names | TUe; Testosterone undecenoate; 17β-Hydroxyandrost-4-en-3-one 17β-(undec-10-enoate) |
Routes of administration | Intramuscular injection |
Drug class | Androgen; Anabolic steroid; Androgen ester |
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ECHA InfoCard | 100.045.099 |
Chemical and physical data | |
Formula | C30H46O3 |
Molar mass | 454.695 g·mol−1 |
3D model (JSmol) | |
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See also
References
- Shapiro S, Weinburg K, Freedman L (1956). "Notes - Long-Acting Androgens". The Journal of Organic Chemistry. 21 (11): 1300–1302. doi:10.1021/jo01117a602. ISSN 0022-3263.
- Gould D, Finckenor L, Hershberg EB, Cassidy J, Perlman PL (1957). "Long-acting Testosterone Esters. Some Considerations on their Biological Utilization1". Journal of the American Chemical Society. 79 (16): 4472–4475. doi:10.1021/ja01573a061. ISSN 0002-7863.
- US 2855341, Meier, Rolf; Wettstein, Albert & Lang, Emil, "Testosterone compositions", published 1958-10-07, assigned to Ciba pharmaceutical Products, Inc.
- Schuermann H, Doepfmer R (1960). Fertilitätsstörungen beim Manne. Springer-Verlag. pp. 260–. ISBN 978-3-642-94784-1.
- Ufer J (1960). Hormontherapie in der Frauenheilkunde: Grundlagen und Praxis. Gruyter. p. 153. ISBN 9783111138770.
- Aakvaag A, Vogt JH (March 1969). "Plasma testosterone values in different forms of testosterone treatment". Acta Endocrinologica. 60 (3): 537–42. doi:10.1530/acta.0.0600537. PMID 5395873.
Triolandren®, for intramuscular use, kindly supplied by Ciba, Basel, through Kobro 8c Co., Oslo, containing three different testosterone esters, in the following amounts of testosterone equivalents per ml oil: propionate 20 mg; valerate 80 mg; undecylenate 150 mg.
- Zachmann M, Prader A (January 1970). "Anabolic and androgenic effect of testosterone in sexually immature boys and its dependency on growth hormone". The Journal of Clinical Endocrinology and Metabolism. 30 (1): 85–95. doi:10.1210/jcem-30-1-85. PMID 4311616.
Triolandren, CIBA; 250 mg of this preparation contains 20 mg of testosterone propionate, 80 mg of testosterone-n-valerianate, and 150 mg of testosterone undecylenate—250 mg thus contains 173.8 mg of testosterone; the remaining 76.2 mg consists of the ester components [...]
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