2017 Uganda Marburg virus outbreak

The 2017 Uganda Marburg virus outbreak was confirmed by the World Health Organization (WHO) on 20 October 2017 after there had been an initial fatality due to the virus.[6]

Uganda Marburg outbreak 2017
Initial case= 25 September 2017[1]
Declared ended= 2 December 2017[2]
Uganda
Uganda
Uganda (orthographic projection)
Confirmed cases[3]2
Probable cases[4]1
Deaths[5]3

The Ugandan Ministry of Health indicated that an individual had died of the virus on 19 October; the following day, 20 October, WHO released a press statement regarding the matter. The eastern part of the country is the affected area where the cases have occurred.[1][3] On 22 October, it was reported that 55 individuals were under surveillance for the virus.[7] On 25 October, the number of individuals rose to 155 in terms of contact tracing[8]

Virology and epidemiology
Main article: Viral hemorrhagic fever
Marburg virus

According to the Centers for Disease Control and Prevention (CDC), the Marburg virus was first recognised in 1967.[9] In terms of diagnosis the presentation is similar to malaria or typhoid fever and therefore not easy to identify (diagnose).[10]

The Marburg virus is considered a filovirus, which is the same as the Ebola virus in terms of viral classification.[11] According to Mehedi, et al. macrophages, monocytes, and dendritic cells, are what the virus attacks due to their importance in the human bodies normal mechanism[12]

According to the World Health Organization there is currently no treatment for the disease.[13] As of 11 November 2017, according to the Ministry of Health no new cases have been reported to this point[14] the report originates from Kampala.

On 8 December the World Health Organization declared the end to the outbreak in the country of Uganda due to two 21-day quarantine periods[15]

Other outbreaks
Main article: Marburg virus disease § Epidemiology


The table lists a subset of the Marburg virus disease outbreaks, which have occurred specifically in Uganda:

Marburg virus disease outbreaks in Uganda
Year Country Virus Human cases Human deaths Case fatality rate Reference
2007  Uganda MARV & RAVV 2 1 50% [16]
2008  Uganda  Netherlands  United States MARV 2 1 50% [17]
2012  Uganda MARV 18 9 50% [18]
2014  Uganda MARV 1 1 100% [19]
2017  Uganda MARV 3 3 100% [2]

See also

References
  1. Athumani, Halima. "Uganda Confirms 1 Death From Ebola-like Marburg Virus". VOA. Retrieved 21 October 2017.
  2. "Uganda controls deadly Marburg fever outbreak, WHO says". ABC News. Archived from the original on 8 December 2017. Retrieved 8 December 2017.
  3. "Ebola-like Marburg virus kills two in Uganda". Daily Nation. Retrieved 21 October 2017.
  4. "Marburg virus disease – Uganda and Kenya". World Health Organization. Archived from the original on 17 November 2017. Retrieved 16 November 2017.
  5. "Uganda – Marburg Virus Disease (DG ECHO, Ministry of Health)( ECHO Daily Flash of 06 November 2017)". ReliefWeb. 6 November 2017. Retrieved 6 November 2017.
  6. "WHO supports containment of rare virus on Uganda-Kenya border". World Health Organization. Retrieved 21 October 2017.
  7. "Marburg: 55 people under surveillance". The Observer – Uganda. Retrieved 23 October 2017.
  8. "Marburg virus disease – Uganda". World Health Organization. Archived from the original on 26 October 2017. Retrieved 16 November 2017.
  9. "Ebola & Marburg | NIH: National Institute of Allergy and Infectious Diseases". www.niaid.nih.gov. Retrieved 21 October 2017.
  10. "Marburg Hemorrhagic Fever (Marburg HF) | CDC". www.cdc.gov. Retrieved 21 October 2017.
  11. Bente, Dennis; Gren, Jason; Strong, James E.; Feldmann, Heinz (2009). "Disease modeling for Ebola and Marburg viruses". Disease Models & Mechanisms. 2 (1–2): 12–17. doi:10.1242/dmm.000471. ISSN 1754-8403. PMC 2615158. PMID 19132113.
  12. Mehedi, Masfique; Groseth, Allison; Feldmann, Heinz; Ebihara, Hideki (2011). "Clinical aspects of Marburg hemorrhagic fever". Future Virology. 6 (9): 1091–1106. doi:10.2217/fvl.11.79. ISSN 1746-0794. PMC 3201746. PMID 22046196.
  13. "Marburg virus disease". World Health Organization. Retrieved 29 October 2017.
  14. "Press Release | Ministry of Health". health.go.ug. Retrieved 16 November 2017.
  15. "Uganda ends Marburg virus disease outbreak". ReliefWeb. Retrieved 8 December 2017.
  16. "WHO | Marburg haemorrhagic fever in Uganda". www.who.int. Archived from the original on 8 October 2014. Retrieved 23 October 2017.
  17. "Imported Case of Marburg Hemorrhagic Fever --- Colorado, 2008". cdc.gov. Retrieved 23 October 2017.
  18. "WHO | Marburg haemorrhagic fever in Uganda – update". www.who.int. Archived from the original on 10 August 2014. Retrieved 29 October 2017.
  19. "WHO | Marburg virus disease – Uganda". www.who.int. Archived from the original on 17 November 2014. Retrieved 29 October 2017.

Further reading
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