Cosavirus

Cosavirus is a genus of viruses in the order Picornavirales, in the family Picornaviridae. Human serve as natural hosts. There are 5 species in this genus.[1][2]

Cosavirus
Virus classification
(unranked): Virus
Realm: Riboviria
Kingdom: Orthornavirae
Phylum: Pisuviricota
Class: Pisoniviricetes
Order: Picornavirales
Family: Picornaviridae
Genus: Cosavirus

It is unclear whether cosaviruses are connected to gastroenteritis in humans.[3]

Taxonomy

The genus contains the following five species:[2]

  • Cosavirus A
  • Cosavirus B
  • Cosavirus C
  • Cosavirus D
  • Cosavirus E

Structure

Viruses in Cosavirus are non-enveloped, with icosahedral, spherical, and round geometries, and T=pseudo3 symmetry. The diameter is around 30 nm. Genomes are linear and non-segmented, around 7-8kb in length.[1]

GenusStructureSymmetryCapsidGenomic arrangementGenomic segmentation
CosavirusIcosahedralPseudo T=3Non-envelopedLinearMonopartite

Life cycle

Viral replication is cytoplasmic. Entry into the host cell is achieved by attachment of the virus to host receptors, which mediates endocytosis. Replication follows the positive stranded RNA virus replication model. Positive stranded RNA virus transcription is the method of transcription. Translation takes place by ribosomal skipping. The virus exits the host cell by lysis, and viroporins. Human serve as the natural host. Transmission routes are fecal-oral.[1]

GenusHost detailsTissue tropismEntry detailsRelease detailsReplication siteAssembly siteTransmission
CosavirusHumanNoneCell receptor endocytosisUnknownCytoplasmCytoplasmUnknown

References
  1. "Viral Zone". ExPASy. Retrieved 13 August 2015.
  2. "Virus Taxonomy: 2020 Release". International Committee on Taxonomy of Viruses (ICTV). March 2021. Retrieved 20 May 2021.
  3. "Newly Identified Viruses in Human Gastroenteritis". The Pediatric Infectious Disease Journal. January 2016. Archived from the original on 17 June 2016. Retrieved 8 March 2020.
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