Gammapapillomavirus

Gammapapillomavirus is a genus of viruses, in the family Papillomaviridae.[1] Human serve as natural hosts. There are 27 species in this genus. Diseases associated with this genus include: warts, papilloma.[2][3]

Gammapapillomavirus
Virus classification
(unranked): Virus
Realm: Monodnaviria
Kingdom: Shotokuvirae
Phylum: Cossaviricota
Class: Papovaviricetes
Order: Zurhausenvirales
Family: Papillomaviridae
Genus: Gammapapillomavirus

Taxonomy

The following 27 species are assigned to the genus:[3]

  • Gammapapillomavirus 1
  • Gammapapillomavirus 2
  • Gammapapillomavirus 3
  • Gammapapillomavirus 4
  • Gammapapillomavirus 5
  • Gammapapillomavirus 6
  • Gammapapillomavirus 7
  • Gammapapillomavirus 8
  • Gammapapillomavirus 9
  • Gammapapillomavirus 10
  • Gammapapillomavirus 11
  • Gammapapillomavirus 12
  • Gammapapillomavirus 13
  • Gammapapillomavirus 14
  • Gammapapillomavirus 15
  • Gammapapillomavirus 16
  • Gammapapillomavirus 17
  • Gammapapillomavirus 18
  • Gammapapillomavirus 19
  • Gammapapillomavirus 20
  • Gammapapillomavirus 21
  • Gammapapillomavirus 22
  • Gammapapillomavirus 23
  • Gammapapillomavirus 24
  • Gammapapillomavirus 25
  • Gammapapillomavirus 26
  • Gammapapillomavirus 27

Structure

Viruses in Gammapapillomavirus are non-enveloped, with icosahedral geometries, and T=7 symmetry. The diameter is around 60 nm. Genomes are circular, around 8kb in length.[2]

GenusStructureSymmetryCapsidGenomic arrangementGenomic segmentation
GammapapillomavirusIcosahedralT=7Non-envelopedCircularMonopartite

Life cycle

Viral replication is nuclear. Entry into the host cell is achieved by attachment of the viral proteins to host receptors, which mediates endocytosis. Replication follows the dsDNA bidirectional replication model. DNA-templated transcription, with some alternative splicing mechanism is the method of transcription. The virus exits the host cell by nuclear envelope breakdown. Human serve as the natural host. Transmission routes are contact.[2]

GenusHost detailsTissue tropismEntry detailsRelease detailsReplication siteAssembly siteTransmission
GammapapillomavirusHumansEpithelial: mucous; epithelial: skinCell receptor endocytosisLysisNucleusNucleusContact

References
  1. Van Doorslaer, K; Chen, Z; Bernard, HU; Chan, PKS; DeSalle, R; Dillner, J; Forslund, O; Haga, T; McBride, AA; Villa, LL; Burk, RD; ICTV Report Consortium (August 2018). "ICTV Virus Taxonomy Profile: Papillomaviridae". The Journal of General Virology. 99 (8): 989–990. doi:10.1099/jgv.0.001105. PMC 6171710. PMID 29927370.
  2. "Viral Zone". ExPASy. Retrieved 15 June 2015.
  3. "Virus Taxonomy: 2020 Release". International Committee on Taxonomy of Viruses (ICTV). March 2021. Retrieved 10 May 2021.
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