Respirovirus

Respirovirus is a genus of viruses in the order Mononegavirales, in the family Paramyxoviridae.[2] Rodents and human serve as natural hosts. There are seven species in this genus.[3] Diseases associated with this genus include: croup and other acute febrile respiratory tract infections.[4]

Respirovirus
Illustration of a respirovirus
Virus classification
(unranked): Virus
Realm: Riboviria
Kingdom: Orthornavirae
Phylum: Negarnaviricota
Class: Monjiviricetes
Order: Mononegavirales
Family: Paramyxoviridae
Subfamily: Orthoparamyxovirinae
Genus: Respirovirus
Species
Synonyms[1]
  • Paramyxovirus

Structure

Respirovirions are enveloped, with spherical geometries. The diameter is around 150 nm. Respirovirus genomes are linear, around 15kb in length. The genome codes for 8 proteins.[3][4]

GenusStructureSymmetryCapsidGenomic arrangementGenomic segmentation
RespirovirusSphericalEnvelopedLinearMonopartite

Life cycle

Viral replication is cytoplasmic. Entry into the host cell is achieved by virus attaches to host cell. Replication follows the negative stranded RNA virus replication model. Negative stranded RNA virus transcription, using polymerase stuttering is the method of transcription. Translation takes place by leaky scanning, and ribosomal shunting. The virus exits the host cell by budding. Rodents and human serve as the natural host. Transmission routes are respiratory.[3][4]

GenusHost detailsTissue tropismEntry detailsRelease detailsReplication siteAssembly siteTransmission
RespirovirusRodents; humansNoneGlycoproteinBuddingCytoplasmCytoplasmAerosols

References
  1. Pringle, C. R. (1998). "Virus taxonomy-San Diego 1998" (PDF). Archives of Virology. 143 (7): 1449–59. doi:10.1007/s007050050389. PMID 9742051.
  2. Rima, B; Balkema-Buschmann, A; Dundon, WG; Duprex, WP; Easton, A; Fouchier, R; Kurath, G; Lamb, R; Lee, B; Rota, P; Wang, L; ICTV Report Consortium (December 2019). "ICTV Virus Taxonomy Profile: Paramyxoviridae". The Journal of General Virology. 100 (12): 1593–1594. doi:10.1099/jgv.0.001328. PMID 31609197.
  3. "Virus Taxonomy: 2020 Release". International Committee on Taxonomy of Viruses (ICTV). March 2021. Retrieved 18 May 2021.
  4. "Viral Zone". ExPASy. Retrieved 15 June 2015.

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