A-232

A-232 is an organophosphate nerve agent.[1] It was developed in the Soviet Union under the FOLIANT program and is one of the group of compounds referred to as Novichok agents that were revealed by Vil Mirzayanov. A-232 is reportedly slightly less potent as a nerve agent compared to some of the other compounds in the series such as A-230 and A-234, having similar potency to the older nerve agent VR. However it proved to be the most versatile agent as it was chemically stable and remained a volatile liquid over a wide temperature range, making it able to be used in standard chemical munitions without requiring special delivery mechanisms to be developed.[2][3][4]

A-232
Names
IUPAC name
methoxy-(1-(diethylamino)ethylidene)phosphoramidofluoridate
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
  • InChI=1/C7H16FN2O2P/c1-5-10(6-2)7(3)9-13(8,11)12-4/h5-6H2,1-4H3/b9-7+
    Key: BBTXAVJVSQSXHZ-VQHVLOKHNA-N
  • CCN(CC)C(\C)=N\P(F)(=O)OC
Properties
C7H16FN2O2P
Molar mass 210.189 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

A-232 has been added to Schedule 1 of the Annex on Chemicals of the Chemical Weapons Convention as of June 2020, and it has been explicitly named as an example compound for schedule 1.A.14.[5][6] For chemicals listed in Schedule 1, the most stringent declaration and verification measures are in place combined with far-reaching limits and bans on production and use. It is notable to say that Annex 1 does not explicitly relate this structure to the name A-232, just add this particular structure to the prohibited compounds section.

See also

References
  1. Stone, R. (19 March 2018). "U.K. attack shines spotlight on deadly nerve agent developed by Soviet scientists". Science. doi:10.1126/science.aat6324.
  2. Mirzayanov VS (2008). State Secrets: An Insider's Chronicle of the Russian Chemical Weapons Program. Outskirts Press. ISBN 978-1-4327-2566-2.
  3. Vásárhelyi G, Földi L (2007). "History of Russia's chemical weapons" (PDF). AARMS. 6 (1): 135–146. Archived from the original (PDF) on 2018-03-14.
  4. Franca TC, Kitagawa DA, Cavalcante SF, da Silva JA, Nepovimova E, Kuca K (March 2019). "Novichoks: The Dangerous Fourth Generation of Chemical Weapons". International Journal of Molecular Sciences. 20 (5): 1222. doi:10.3390/ijms20051222. PMC 6429166. PMID 30862059.
  5. "S/1821/2019/Rev.1 Note by the Technical Secretariat Guidance for States Parties on Article VI Declaration Obligations and Inspections Following Entry Into Force of Changes to Schedule 1 of the Annex on Chemicals to the Chemical Weapons Convention" (PDF). 14 January 2020.
  6. "Schedule 1". Organisation for the Prohibition of Chemical Weapons (OPCW). Retrieved 2020-07-26.
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