TL-599

TL-599
Names
	Preferred IUPAC name 4-[(Dimethylcarbamoyl)oxy]-N,N,N-trimethyl-2-(propan-2-yl)anilinium iodide
	Other names SB-8
Identifiers
CAS Number	63981-53-3;
3D model (JSmol)	Interactive image;
ChemSpider	41823;
PubChem CID	45961;
UNII	SD9T6QM997;
CompTox Dashboard (EPA)	DTXSID10981619 ;
	InChI InChI=1S/C15H25N2O2.HI/c1-11(2)13-10-12(19-15(18)16(3)4)8-9-14(13)17(5,6)7;/h8-11H,1-7H3;1H/q+1;/p-1 Key: DBMNNBLVHXQGOH-UHFFFAOYSA-M;
	SMILES CC(C)c1cc(ccc1[N+](C)(C)C)OC(=O)N(C)C.[I-];
Properties
Chemical formula	C15H25IN2O2
Molar mass	392.281 g·mol−1
Hazards
	Lethal dose or concentration (LD, LC):
LD50 (median dose)	75 μg/kg (subcutaneous, mice)[1]; 168 μg/kg (intraperitoneal, mice)[1]; 75 μg/kg (mice, subcutaneous)[2]
LDLo (lowest published)	100 μg/kg (guinea pigs, subcutaneous)[1]
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

TL-599, also known as SB-8, is an extremely potent carbamate acetylcholinesterase inhibitor.[1][2]

References

Chemical Warfare Agents, and Related Chemical Problems. Parts I-II.
Stevens, Joseph R.; Beutel, Ralph H. (January 1941). "Physostigmine Substitutes". Journal of the American Chemical Society. 63 (1): 308–311. doi:10.1021/ja01846a078.

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