Estrone tetraacetylglucoside

Estrone tetraacetylglucoside (brand name Glucovex, Glycovex) is a semisynthetic, steroidal estrogen.[1] It is an estrogen ester, specifically, an ester of estrone.[1] The drug was marketed since at least 1942.[2]

Estrone tetraacetylglucoside
Identifiers
IUPAC name
  • [(2R,3R,4S,5R,6S)-3,4,5-triacetyloxy-6-{[(8R,9S,13S,14S)-13-methyl-17-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-yl]oxy}oxan-2-yl]methyl acetate
CAS Number
PubChem CID
ChemSpider
Chemical and physical data
FormulaC32H40O11
Molar mass600.661 g·mol−1
3D model (JSmol)
SMILES
  • CC(=O)OCC1OC(Oc2ccc3C4CCC5(C)C(CCC5=O)C4CCc3c2)C(OC(C)=O)C(OC(C)=O)C1OC(C)=O
InChI
  • InChI=1S/C32H40O11/c1-16(33)38-15-26-28(39-17(2)34)29(40-18(3)35)30(41-19(4)36)31(43-26)42-21-7-9-22-20(14-21)6-8-24-23(22)12-13-32(5)25(24)10-11-27(32)37/h7,9,14,23-26,28-31H,6,8,10-13,15H2,1-5H3
  • Key:IMZSXCARTLIDBP-UHFFFAOYSA-N

References
  1. Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. p. 900. ISBN 978-1-4757-2085-3.
  2. Jacobson O (1947). Heredity in breast cancer, a genetic and clinical study of two hundred probands. Københavns universitet. Institut for human arvebiologi og eugenik. Munksgaard. p. 251.


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.