Methestrol dipropionate

Methestrol dipropionate or methoestrol dipropionate (brand name Meprane Dipropionate), also known as promethestrol dipropionate or promethoestrol dipropionate or as dimethylhexestrol dipropionate, is a synthetic nonsteroidal estrogen of the stilbestrol group related to diethylstilbestrol that is or was used clinically.[1][2][3][4][5][6][7][8] It is the dipropionate form of methestrol (or promethestrol), which, in contrast to methestrol dipropionate, was never marketed.[3]

Methestrol dipropionate
Clinical data
Trade namesMeprane Dipropionate
Other namesMethoestrol dipropionate; Metestrol dipropionate; Promethestrol dipropionate; Promethoestrol dipropionate; Dimethylhexestrol dipropionate
Drug classNonsteroidal estrogen; Estrogen ester
Identifiers
IUPAC name
  • [2-methyl-4-[4-(3-methyl-4-propanoyloxyphenyl)hexan-3-yl]phenyl] propanoate
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC26H34O4
Molar mass410.554 g·mol−1
3D model (JSmol)
SMILES
  • CCC(C1=CC(=C(C=C1)OC(=O)CC)C)C(CC)C2=CC(=C(C=C2)OC(=O)CC)C
InChI
  • InChI=1S/C26H34O4/c1-7-21(19-11-13-23(17(5)15-19)29-25(27)9-3)22(8-2)20-12-14-24(18(6)16-20)30-26(28)10-4/h11-16,21-22H,7-10H2,1-6H3
  • Key:ORHVFDBDWJTZIN-UHFFFAOYSA-N

See also

References
  1. Ganellin CR, Triggle DJ (21 November 1996). Dictionary of Pharmacological Agents. CRC Press. pp. 608–. ISBN 978-0-412-46630-4.
  2. Brucker MC, King TL (8 September 2015). Pharmacology for Women's Health. Jones & Bartlett Learning. pp. 640–. ISBN 978-1-284-10811-8.
  3. Ganellin CR, Triggle DJ (21 November 1996). Dictionary of Pharmacological Agents. Taylor & Francis. pp. 1298–. ISBN 978-0-412-46630-4.
  4. Thomas JA, Keenan EJ (6 December 2012). Principles of Endocrine Pharmacology. Springer Science & Business Media. pp. 150–. ISBN 978-1-4684-5036-1.
  5. Prasad A, Sinha AK (1985). Essential of Endocrinology and Reproductive Physiology. Allied Publishers. pp. 85–. GGKEY:HLNJ1BHUKW2.
  6. Modell W (21 November 2013). Drugs in Current Use 1958. Springer. pp. 114–. ISBN 978-3-662-40303-7.
  7. Dubin WR, Stolberg R (6 December 2012). Emergency Psychiatry for the House Officer. Springer Science & Business Media. pp. 155–. ISBN 978-94-011-6690-4.
  8. Raspé G (22 October 2013). Hormones and Embryonic Development: Advances in The Biosciences. Elsevier Science. pp. 141–. ISBN 978-1-4831-5171-7.



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