Trimedoxime bromide

Trimedoxime bromide
Clinical data
Routes of; administration	Intramuscular injection
ATC code	None;
Legal status
Legal status	Experimental; in military use;
Pharmacokinetic data
Elimination half-life	2 hours (mean)
Identifiers
	IUPAC name 1,1′-propane-1,3-diylbis{4-[(E)-(hydroxyimino)methyl]pyridinium} dibromide;
CAS Number	56-97-3;
PubChem CID	5359236;
ChemSpider	4514238;
UNII	ED0GXI9825;
ECHA InfoCard	100.000.276
Chemical and physical data
Formula	C15H18Br2N4O2
Molar mass	446.143 g·mol−1

Trimedoxime bromide (INN), also known as dipyroxime or TMB-4, is an oxime used in the treatment of organophosphate poisoning[1] It is chemically related to pralidoxime.[2]

References

Dhuguru J, Zviagin E, Skouta R (January 2022). "FDA-Approved Oximes and Their Significance in Medicinal Chemistry". Pharmaceuticals. Basel, Switzerland. 15 (1): 66. doi:10.3390/ph15010066. PMC 8779982. PMID 35056123.
Gupta R, Parmar M (2022). "Pralidoxime". StatPearls. Treasure Island (FL): StatPearls Publishing. PMID 32644334.

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[Dhuguru_2022-1] Dhuguru J, Zviagin E, Skouta R (January 2022). "FDA-Approved Oximes and Their Significance in Medicinal Chemistry". Pharmaceuticals. Basel, Switzerland. 15 (1): 66. doi:10.3390/ph15010066. PMC 8779982. PMID 35056123.

[2] Gupta R, Parmar M (2022). "Pralidoxime". StatPearls. Treasure Island (FL): StatPearls Publishing. PMID 32644334.