Trimedoxime bromide

Trimedoxime bromide (INN), also known as dipyroxime or TMB-4, is an oxime used in the treatment of organophosphate poisoning[1] It is chemically related to pralidoxime.[2]

Trimedoxime bromide
Clinical data
Routes of
administration
Intramuscular injection
ATC code
  • None
Legal status
Legal status
  • Experimental; in military use
Pharmacokinetic data
Elimination half-life2 hours (mean)
Identifiers
IUPAC name
  • 1,1-propane-1,3-diylbis{4-[(E)-(hydroxyimino)methyl]pyridinium} dibromide
CAS Number
PubChem CID
ChemSpider
UNII
ECHA InfoCard100.000.276
Chemical and physical data
FormulaC15H18Br2N4O2
Molar mass446.143 g·mol−1

References

  1. Dhuguru J, Zviagin E, Skouta R (January 2022). "FDA-Approved Oximes and Their Significance in Medicinal Chemistry". Pharmaceuticals. Basel, Switzerland. 15 (1): 66. doi:10.3390/ph15010066. PMC 8779982. PMID 35056123.
  2. Gupta R, Parmar M (2022). "Pralidoxime". StatPearls. Treasure Island (FL): StatPearls Publishing. PMID 32644334.


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