Indobufen

Indobufen
Clinical data
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
IUPAC name
  • 2-(4-(1-Oxoisoindolin-2-yl)phenyl)butanoic acid
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.058.496
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Chemical and physical data
FormulaC18H17NO3
Molar mass295.338 g·mol−1
3D model (JSmol)
SMILES
  • O=C(O)C(c1ccc(cc1)N3C(=O)c2ccccc2C3)CC
InChI
  • InChI=1S/C18H17NO3/c1-2-15(18(21)22)12-7-9-14(10-8-12)19-11-13-5-3-4-6-16(13)17(19)20/h3-10,15H,2,11H2,1H3,(H,21,22) ☒N
  • Key:AYDXAULLCROVIT-UHFFFAOYSA-N ☒N
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Indobufen is a platelet aggregation inhibitor.[1] It acts as a reversible cyclooxygenase inhibitor.[2]

References

  1. The Merck Index (12th ed.). p. 4991.
  2. Eligini S, Violi F, Banfi C, Barbieri SS, Brambilla M, Saliola M, et al. (January 2006). "Indobufen inhibits tissue factor in human monocytes through a thromboxane-mediated mechanism". Cardiovascular Research. 69 (1): 218–26. doi:10.1016/j.cardiores.2005.07.013. PMID 16154551.
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