DDEF1
DDEF1 (ArfGAP with SH3 domain, ankyrin repeat and PH domain 1) هوَ بروتين يُشَفر بواسطة جين DDEF1 في الإنسان.[1][2]
المراجع
- "ASAP1, a phospholipid-dependent arf GTPase-activating protein that associates with and is phosphorylated by Src"، Mol Cell Biol، 18 (12): 7038–51، ديسمبر 1998، PMC 109286، PMID 9819391.
- "Entrez Gene: DDEF1 development and differentiation enhancing factor 1"، مؤرشف من الأصل في 05 ديسمبر 2010.
قراءة متعمقة
- "Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."، DNA Res.، 6 (5): 337–45، 2000، doi:10.1093/dnares/6.5.337، PMID 10574462.
- "DEF-1/ASAP1 is a GTPase-activating protein (GAP) for ARF1 that enhances cell motility through a GAP-dependent mechanism."، J. Biol. Chem.، 277 (10): 7962–9، 2002، doi:10.1074/jbc.M109149200، PMID 11773070.
- "Identification of novel SH3 domain ligands for the Src family kinase Hck. Wiskott-Aldrich syndrome protein (WASP), WASP-interacting protein (WIP), and ELMO1."، J. Biol. Chem.، 277 (31): 28238–46، 2002، doi:10.1074/jbc.M202783200، PMID 12029088.
- "The association of ASAP1, an ADP ribosylation factor-GTPase activating protein, with focal adhesion kinase contributes to the process of focal adhesion assembly."، Mol. Biol. Cell، 13 (6): 2147–56، 2002، doi:10.1091/mbc.E02-01-0018، PMC 117631، PMID 12058076.
- "Interaction of POB1, a downstream molecule of small G protein Ral, with PAG2, a paxillin-binding protein, is involved in cell migration."، J. Biol. Chem.، 277 (41): 38618–26، 2002، doi:10.1074/jbc.M203453200، PMID 12149250.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences."، Proc. Natl. Acad. Sci. U.S.A.، 99 (26): 16899–903، 2003، Bibcode:2002PNAS...9916899M، doi:10.1073/pnas.242603899، PMC 139241، PMID 12477932.
- "CrkL directs ASAP1 to peripheral focal adhesions."، J. Biol. Chem.، 278 (8): 6456–60، 2003، doi:10.1074/jbc.M210817200، PMID 12522101.
- "Complete sequencing and characterization of 21,243 full-length human cDNAs."، Nat. Genet.، 36 (1): 40–5، 2004، doi:10.1038/ng1285، PMID 14702039.
- "Expression of AMAP1, an ArfGAP, provides novel targets to inhibit breast cancer invasive activities."، EMBO J.، 24 (5): 963–73، 2005، doi:10.1038/sj.emboj.7600588، PMC 554134، PMID 15719014.
- "DDEF1 is located in an amplified region of chromosome 8q and is overexpressed in uveal melanoma."، Clin. Cancer Res.، 11 (10): 3609–13، 2005، doi:10.1158/1078-0432.CCR-04-1941، PMID 15897555.
- "Regulation of ASAP1 by phospholipids is dependent on the interface between the PH and Arf GAP domains."، Cell. Signal.، 17 (10): 1276–88، 2005، doi:10.1016/j.cellsig.2005.01.007، PMID 16038802.
- "DNA sequence and analysis of human chromosome 8."، Nature، 439 (7074): 331–5، 2006، Bibcode:2006Natur.439..331N، doi:10.1038/nature04406، PMID 16421571.
- "Targeting AMAP1 and cortactin binding bearing an atypical src homology 3/proline interface for prevention of breast cancer invasion and metastasis."، Proc. Natl. Acad. Sci. U.S.A.، 103 (18): 7036–41، 2006، Bibcode:2006PNAS..103.7036H، doi:10.1073/pnas.0509166103، PMC 1459014، PMID 16636290.
- بوابة طب
- بوابة علم الأحياء الخلوي والجزيئي
- بوابة الكيمياء الحيوية
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