PRND
PRND (Prion like protein doppel) هوَ بروتين يُشَفر بواسطة جين PRND في الإنسان.[1]
الوظيفة
المراجع
- "Entrez Gene: PRND prion protein 2 (dublet)"، مؤرشف من الأصل في 05 ديسمبر 2010.
قراءة متعمقة
- "Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel."، J. Mol. Biol.، 292 (4): 797–817، 1999، doi:10.1006/jmbi.1999.3108، PMID 10525406.
- "Perspectives: neurobiology. PrP's double causes trouble."، Science، 286 (5441): 914–5، 1999، doi:10.1126/science.286.5441.914، PMID 10577243.
- "First report of polymorphisms in the prion-like protein gene (PRND): implications for human prion diseases."، Neurosci. Lett.، 286 (2): 144–8، 2000، doi:10.1016/S0304-3940(00)01100-9، PMID 10825657.
- "Expression and structural characterization of the recombinant human doppel protein."، Biochemistry، 39 (44): 13575–83، 2000، doi:10.1021/bi001523m، PMID 11063595.
- "Polymorphisms within the prion-like protein gene (Prnd) and their implications in human prion diseases, Alzheimer's disease and other neurological disorders."، Hum. Genet.، 109 (3): 319–25، 2001، doi:10.1007/s004390100591، PMID 11702213.
- "Doppel-induced cerebellar degeneration in transgenic mice."، Proc. Natl. Acad. Sci. U.S.A.، 98 (26): 15288–93، 2002، doi:10.1073/pnas.251550798، PMC 65022، PMID 11734625.
- "The DNA sequence and comparative analysis of human chromosome 20."، Nature، 414 (6866): 865–71، 2002، doi:10.1038/414865a، PMID 11780052.
- "The human "prion-like" protein Doppel is expressed in both Sertoli cells and spermatozoa."، J. Biol. Chem.، 277 (45): 43071–8، 2003، doi:10.1074/jbc.M206357200، PMID 12200435.
- "Polymorphism at codon 174 of the prion-like protein gene is not associated with sporadic Alzheimer's disease."، Neurosci. Lett.، 332 (3): 213–5، 2003، doi:10.1016/S0304-3940(02)00941-2، PMID 12399017.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences."، Proc. Natl. Acad. Sci. U.S.A.، 99 (26): 16899–903، 2003، doi:10.1073/pnas.242603899، PMC 139241، PMID 12477932.
- "Genomic characterization of the human prion protein (PrP) gene locus."، Mamm. Genome، 13 (12): 696–703، 2003، doi:10.1007/s00335-002-3043-0، PMID 12514748.
- "Prion-like protein Doppel expression is not modified in scrapie-infected cells and in the brains of patients with Creutzfeldt–Jakob disease."، FEBS Lett.، 536 (1–3): 61–5، 2003، doi:10.1016/S0014-5793(03)00012-7، PMID 12586339.
- "NMR structure of the human doppel protein"، J. Mol. Biol.، 326 (5): 1549–57، 2003، doi:10.1016/S0022-2836(02)01471-7، PMID 12595265.
- "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment"، Genome Res.، 13 (10): 2265–70، 2003، doi:10.1101/gr.1293003، PMC 403697، PMID 12975309.
- "The prion-like protein Doppel fails to interact with itself, the prion protein and the 37 kDa/67 kDa laminin receptor in the yeast two-hybrid system"، Biochim. Biophys. Acta، 1689 (1): 1–5، 2004، doi:10.1016/j.bbadis.2004.02.003، PMID 15158907.
- "Human Doppel and prion protein share common membrane microdomains and internalization pathways"، Int. J. Biochem. Cell Biol.، 36 (10): 2016–31، 2005، doi:10.1016/j.biocel.2004.03.002، PMID 15203115.
- "Interaction of Doppel with the full-length laminin receptor precursor protein"، Arch. Biochem. Biophys.، 428 (2): 165–9، 2004، doi:10.1016/j.abb.2004.06.003، PMID 15246873.
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)"، Genome Res.، 14 (10B): 2121–7، 2004، doi:10.1101/gr.2596504، PMC 528928، PMID 15489334.
- "Spatio-developmental distribution of the prion-like protein doppel in Mammalian testis: a comparative analysis focusing on its presence in the acrosome of spermatids"، Biol. Reprod.، 74 (5): 816–23، 2006، doi:10.1095/biolreprod.105.047829، PMID 16421231.
- "The prion-like protein Doppel (Dpl) interacts with the human receptor for activated C-kinase 1 (RACK1) protein"، Anticancer Res.، 26 (6B): 4539–47، 2007، PMID 17201176.
بوابة طب
بوابة الكيمياء الحيوية
بوابة علم الأحياء الخلوي والجزيئي
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