HLA-B5

HLA-B5 (B5) is an HLA-B serotype. B5 is a broad antigen serotype that recognizes the B51 and B52 split antigen serotypes.[1]

3D representation of HLA-B*5101 (blue) displaying HIV immunodominant epitope KM2 (green) PDB: 1e28
B*5101-β2M with bound peptide 1e28
major histocompatibility complex (human), class I, B51
Split antigens HLA-B51, HLA-B52

Serotype

B5, B51, B52 serotype recognition of some HLA B*51 and B*52 allele-group gene products [2]
B*51 B51 B5 B52 Sample
allele % % %size (N)
510196151899
51027336218
510483176
'
B*52 B52 B5 B51 Sample
allele % % %size (N)
520182272823

References

  1. Marsh, S. G.; Albert, E. D.; Bodmer, W. F.; Bontrop, R. E.; Dupont, B.; Erlich, H. A.; Fernández-Viña, M.; Geraghty, D. E.; Holdsworth, R.; Hurley, C. K.; Lau, M.; Lee, K. W.; Mach, B.; Maiers, M.; Mayr, W. R.; Müller, C. R.; Parham, P.; Petersdorf, E. W.; Sasazuki, T.; Strominger, J. L.; Svejgaard, A.; Terasaki, P. I.; Tiercy, J. M.; Trowsdale, J. (2010). "Nomenclature for factors of the HLA system, 2010". Tissue Antigens. 75 (4): 291–455. doi:10.1111/j.1399-0039.2010.01466.x. PMC 2848993. PMID 20356336.
  2. Robinson J, Waller MJ, Fail SC, Marsh SG (2006). "The IMGT/HLA and IPD databases". Hum. Mutat. 27 (12): 1192–9. doi:10.1002/humu.20406. PMID 16944494.
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