HLA-B67
HLA-B67 (B67) is an HLA-B serotype. The serotype identifies the more common HLA-B*67 gene products.[1] B67 is region specific recombinant haplotype formed by the gene conversion of B*39, an allele common along the Northwest Pacific Rim (Taiwan, Japan, Korea, Coastal Siberia), and B7, B22, or B27.[2] (For terminology help see: HLA-serotype tutorial)
major histocompatibility complex (human), class I, B67 | ||
| Alleles | B*6701 | |
| Structure (See HLA-B) | ||
| Symbol(s) | HLA-B | |
| EBI-HLA | B*6701 | |
| Locus | chr.6 6p21.31 | |
Serotype
| B*67 | B67 | Other | Sample |
| allele | % | % | size (N) |
| 6701 | 32 | 62 | 81 |
By allele
| Japan |  |
| Taiwan |  |
| Heilongjiang province, China (Harbin city) |  |
| Beijing China |  |
| Shandong peninsula |  |
| freq | ||
| ref. | Population | (%) |
| [4] | Osaka Region (Japan) | 2.6 |
| [4] | Hakka (Taiwan) | 1.8 |
| [4] | Japan (5) | 1.7 |
| [4] | Harbin Man (China) | 1.7 |
| [4] | Beijing (China) | 1.5 |
| [4] | Linqu (Shandong, China) | 1.1 |
| [4] | Siraya (Taiwan) | 1.0 |
| [4] | Portugal South | 1.0 |
| [4] | Oold (Mongolia) | 1.0 |
| [4] | American Samoa | 1.0 |
| [4] | Pazeh (Taiwan) | 0.9 |
| [4] | South Korea (3) | 0.9 |
| [4] | N. Korean (Harbin,China) | 0.8 |
| [4] | Arratia Basque (Spain) | 0.6 |
| [4] | Tarialan Khoton (Mongolia) | 0.6 |
| [4] | Shanghai (China) | 0.6 |
| [4] | Natal Zulu (South African) | 0.5 |
| [4] | Yunnan Han (China) | 0.5 |
| [4] | Turkey | 0.4 |
| [4] | Southern Han (China) | 0.4 |
| [4] | Tuva (Russia) | 0.3 |
| [4] | Chinese (Hong Kong, China) | 0.1 |
References
- Marsh, S. G.; Albert, E. D.; Bodmer, W. F.; Bontrop, R. E.; Dupont, B.; Erlich, H. A.; Fernández-Viña, M.; Geraghty, D. E.; Holdsworth, R.; Hurley, C. K.; Lau, M.; Lee, K. W.; Mach, B.; Maiers, M.; Mayr, W. R.; Müller, C. R.; Parham, P.; Petersdorf, E. W.; Sasazuki, T.; Strominger, J. L.; Svejgaard, A.; Terasaki, P. I.; Tiercy, J. M.; Trowsdale, J. (2010). "Nomenclature for factors of the HLA system, 2010". Tissue Antigens. 75 (4): 291–455. doi:10.1111/j.1399-0039.2010.01466.x. PMC 2848993. PMID 20356336.
- Little AM, Domena JD, Hildebrand WH, et al. (1994). "HLA-B67: a member of the HLA-B16 family that expresses the ME1 epitope". Tissue Antigens. 43 (1): 38–43. doi:10.1111/j.1399-0039.1994.tb02294.x. PMID 7517584.
- derived from IMGT/HLA
- Middleton D, Menchaca L, Rood H, Komerofsky R (2003). "New allele frequency database: http://www.allelefrequencies.net". Tissue Antigens. 61 (5): 403–7. doi:10.1034/j.1399-0039.2003.00062.x. PMID 12753660.
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