Substituted piperazine

Substituted piperazines are a class of chemical compounds based on a piperazine core. Some are used as recreational drugs and some are used in scientific research.

List of substituted piperazines

Benzylpiperazines

Befuraline, fipexide, and piberaline produce benzylpiperazine as a metabolite.

Phenylpiperazines

ortho-Substituted

Enpiprazole is known to produce oCPP as a metabolite.

Enciprazine was initially anticipated to produce oMeOPP as a metabolite, but this turned out not to be the case.

meta-Substituted

Trazodone, nefazodone, mepiprazole, and others produce mCPP as a metabolite.

para-Substituted

Multiple substitutions

Others

  • 1-Phenylpiperazine (PP)

Other arylpiperazines

  • 1-(1-Naphthyl)piperazine (1-NP)
  • 1-(2-Pyrimidinyl)piperazine (1-PP)
  • ORG-12962 (1-(5-trifluoromethyl-6-chloropyridin-2-yl)piperazine)
  • Quipazine (2-piperazin-1-ylquinoline)

Many azapirones such as buspirone, gepirone, and tandospirone produce 1-PP as a metabolite.

See also

References


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