Trimazosin

Trimazosin
Clinical data
ATC code
Identifiers
IUPAC name
  • (2-Hydroxy-2-methylpropyl) 4-(4-amino-6,7,8-trimethoxyquinazolin-2-yl)piperazine-1-carboxylate
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.047.924
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Chemical and physical data
FormulaC20H29N5O6
Molar mass435.481 g·mol−1
3D model (JSmol)
SMILES
  • O=C(OCC(O)(C)C)N3CCN(c1nc(N)c2c(n1)c(OC)c(OC)c(OC)c2)CC3
InChI
  • InChI=1S/C20H29N5O6/c1-20(2,27)11-31-19(26)25-8-6-24(7-9-25)18-22-14-12(17(21)23-18)10-13(28-3)15(29-4)16(14)30-5/h10,27H,6-9,11H2,1-5H3,(H2,21,22,23) ☒N
  • Key:YNZXWQJZEDLQEG-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Trimazosin is a sympatholytic alpha-1 blocker.[1][2]

References

  1. ↑ van Kalken CK, van der Meulen J, Oe PL, Vriesendorp R, Donker AJ (1986). "Pharmacokinetics of trimazosin and its effects on blood pressure, renal function and proteinuria during short-term therapy of patients with impaired renal function and hypertension". Eur. J. Clin. Pharmacol. 31 (1): 63–8. doi:10.1007/BF00870988. PMID 3780829. S2CID 19123951.
  2. ↑ U.S. Patent 3,669,968



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