Metipranolol

Metipranolol
Clinical data
Trade namesOptipranolol
AHFS/Drugs.comMicromedex Detailed Consumer Information
MedlinePlusa601078
ATC code
Identifiers
IUPAC name
  • (RS)-4-{[-2-hydroxy-3-(isopropylamino)propyl]oxy}-2,3,6-trimethylphenyl acetate
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.041.031
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Chemical and physical data
FormulaC17H27NO4
Molar mass309.406 g·mol−1
3D model (JSmol)
ChiralityRacemic mixture
SMILES
  • O=C(Oc1c(c(c(OCC(O)CNC(C)C)cc1C)C)C)C
InChI
  • InChI=1S/C17H27NO4/c1-10(2)18-8-15(20)9-21-16-7-11(3)17(22-14(6)19)13(5)12(16)4/h7,10,15,18,20H,8-9H2,1-6H3 checkY
  • Key:BQIPXWYNLPYNHW-UHFFFAOYSA-N checkY
  (verify)

Metipranolol (OptiPranolol, Betanol, Disorat, Trimepranol) is a non-selective beta blocker used in eye drops to treat glaucoma. It is rapidly metabolized into desacetylmetipranolol.[1]

References

  1. Maffei Facino R, Bertuletti R, Carini M, Tofanetti O (1980). "In vitro metabolism of methypranolol by rat liver". Analytical Chemistry Symposia Series. 4 (6): 217–223.
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