Butofilolol

Butofilolol
Clinical data
Other namesCM-6805
ATC code
  • none
Identifiers
IUPAC name
  • (RS)-1-[2-[3-(tert-butylamino)-2-hydroxypropoxy]-5-fluorophenyl]butan-1-one
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
ECHA InfoCard100.055.892
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Chemical and physical data
FormulaC17H26FNO3
Molar mass311.397 g·mol−1
3D model (JSmol)
SMILES
  • Fc1ccc(OCC(O)CNC(C)(C)C)c(c1)C(=O)CCC
InChI
  • InChI=1S/C17H26FNO3/c1-5-6-15(21)14-9-12(18)7-8-16(14)22-11-13(20)10-19-17(2,3)4/h7-9,13,19-20H,5-6,10-11H2,1-4H3 checkY
  • Key:NMBNQRJDEPOXCP-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Butofilolol (trade name Cafide) is a beta-blocker drug for the treatment of essential hypertension (high blood pressure).[1][2] It is not known to be marketed anywhere.

References

  1. Houin G, Barre J, Jeanniot JP, Ledudal P, Cautreels W, Tillement JP (1984). "Pharmacokinetics of butofilolol (CAFIDE) after repeated oral administration in man". International Journal of Clinical Pharmacology Research. 4 (3): 175–83. PMID 6149195.
  2. Toussain P, Gay G, Debry G (June 1983). "[Long-term hypotensive treatment by butofilolol]". Annales de Cardiologie et d'Angeiologie. 32 (4): 277–83. PMID 6412614.
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