AP-238

AP-238
Identifiers
IUPAC name
  • 1-[(2R,6S)-2,6-dimethyl-4-[(E)-3-phenylprop-2-enyl]piperazin-1-yl]propan-1-one
CAS Number
PubChem CID
UNII
Chemical and physical data
FormulaC18H26N2O
Molar mass286.419 g·mol−1
3D model (JSmol)
SMILES
  • CCC(=O)N1[C@@H](CN(C[C@@H]1C)C/C=C/C2=CC=CC=C2)C
InChI
  • InChI=1S/C18H26N2O/c1-4-18(21)20-15(2)13-19(14-16(20)3)12-8-11-17-9-6-5-7-10-17/h5-11,15-16H,4,12-14H2,1-3H3/b11-8+/t15-,16+
  • Key:JELNWDOXWGBBLO-QJBCGIKSSA-N

AP-238 is an opioid designer drug related to drugs such as azaprocin and bucinnazine, with around the same potency as morphine. It was first discovered in Italy in the 1960s but was never marketed,[1] subsequently appearing on the illicit market around 2020 and being detected in both Slovenia and the USA.[2][3]

See also

References

  1. ↑ Cignarella G, Testa E (May 1968). "2,6-Dialkylpiperazines. IV. 1-Propionyl-4-substituted cis-2,6-dimethylpiperazines structurally related to the analgetic 8-acyl-3,8-diazabicyclo[3.2.1]octanes". Journal of Medicinal Chemistry. 11 (3): 592–4. doi:10.1021/jm00309a039. PMID 5656502.
  2. ↑ "Analytical Report. AP-238. 1‐{2,6‐dimethyl‐4‐[(2E)‐3‐phenylprop‐2‐en‐1‐yl]piperazin‐1‐yl}propan‐1‐one" (PDF). Nacionalni Forenzični Laboratorij. 20 October 2020.
  3. ↑ "AP-238" (PDF). NPS Discovery at CFSRE. Center for Forensic Science Research and Education (CFSRE). 11 November 2020.


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