LPK-26

LPK-26
Identifiers
IUPAC name
  • 2-(3,4-dichlorophenyl)-N-[(2S)-1-(2,5-dihydropyrrol-1-yl)-3-methylbutan-2-yl]-N-methylacetamide
CAS Number
PubChem CID
ChemSpider
ECHA InfoCard100.161.432
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Chemical and physical data
FormulaC18H24Cl2N2O
Molar mass355.30 g·mol−1
3D model (JSmol)
SMILES
  • CC(C)[C@@H](CN1CC=CC1)N(C)C(=O)CC2=CC(=C(C=C2)Cl)Cl
InChI
  • InChI=1S/C18H24Cl2N2O/c1-13(2)17(12-22-8-4-5-9-22)21(3)18(23)11-14-6-7-15(19)16(20)10-14/h4-7,10,13,17H,8-9,11-12H2,1-3H3/t17-/m1/s1 ☒N
  • Key:QFAIAMMFKKYCTL-QGZVFWFLSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

LPK-26 is a potent and selective κ-opioid agonist, and has analgesic effects.[1]

References

  1. ↑ Tao YM, Li QL, Zhang CF, Xu XJ, Chen J, Ju YW, Chi ZQ, Long YQ, Liu JG (April 2008). "LPK-26, a novel kappa-opioid receptor agonist with potent antinociceptive effects and low dependence potential". European Journal of Pharmacology. 584 (2–3): 306–11. doi:10.1016/j.ejphar.2008.02.028. PMID 18353307.


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