Terbequinil

Terbequinil (SR-25776) is a stimulant and nootropic drug which acts as a partial inverse agonist at benzodiazepine sites on the GABAA receptor. In human trials it was found to partially reverse the sedative and amnestic effects of the hypnotic drug triazolam with only slight effects when administered by itself.[1]

Terbequinil
Clinical data
ATC code
  • none
Identifiers
IUPAC name
  • 1-(methoxymethyl)-4-oxo-N-propylquinoline-3-carboxamide
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC15H18N2O3
Molar mass274.320 g·mol−1
3D model (JSmol)
SMILES
  • CCCNC(=O)C1=CN(C2=CC=CC=C2C1=O)COC
InChI
  • InChI=1S/C15H18N2O3/c1-3-8-16-15(19)12-9-17(10-20-2)13-7-5-4-6-11(13)14(12)18/h4-7,9H,3,8,10H2,1-2H3,(H,16,19) Y
  • Key:RIPDGZHPNKQLDC-UHFFFAOYSA-N Y
 NY (what is this?)  (verify)

See also

References
  1. Warot D, Danjou P, Douillet P, Keane P, Puech AJ (1994). "Cognitive impairments induced by triazolam in healthy volunteers: antagonism by a partial inverse agonist of benzodiazepine receptor". Therapie. 49 (1): 23–6. PMID 8091361.
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