HIF1AN
HIF1AN (Hypoxia inducible factor 1 subunit alpha inhibitor) هوَ بروتين يُشَفر بواسطة جين HIF1AN في الإنسان.[1][2]
المراجع
- "Entrez Gene: HIF1AN hypoxia-inducible factor 1, alpha subunit inhibitor"، مؤرشف من الأصل في 05 ديسمبر 2010.
- "FIH-1: a novel protein that interacts with HIF-1α and VHL to mediate repression of HIF-1 transcriptional activity"، Genes Dev، 15 (20): 2675–86، أكتوبر 2001، doi:10.1101/gad.924501، PMC 312814، PMID 11641274.
قراءة متعمقة
- "Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch"، Science، 295 (5556): 858–61، 2002، doi:10.1126/science.1068592، PMID 11823643.
- "Structural basis for recruitment of CBP/p300 by hypoxia-inducible factor-1α"، Proc. Natl. Acad. Sci. U.S.A.، 99 (8): 5367–72، 2002، doi:10.1073/pnas.082117899، PMC 122775، PMID 11959990.
- "Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family"، J. Biol. Chem.، 277 (29): 26351–5، 2002، doi:10.1074/jbc.C200273200، PMID 12042299.
- "FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor"، Genes Dev.، 16 (12): 1466–71، 2002، doi:10.1101/gad.991402، PMC 186346، PMID 12080085.
- "Structure of factor-inhibiting hypoxia-inducible factor 1: An asparaginyl hydroxylase involved in the hypoxic response pathway"، Proc. Natl. Acad. Sci. U.S.A.، 99 (24): 15351–6، 2003، doi:10.1073/pnas.202614999، PMC 137720، PMID 12432100.
- "Structure of factor-inhibiting hypoxia-inducible factor (HIF) reveals mechanism of oxidative modification of HIF-1 alpha"، J. Biol. Chem.، 278 (3): 1802–6، 2003، doi:10.1074/jbc.C200644200، PMID 12446723.
- "Structure of human FIH-1 reveals a unique active site pocket and interaction sites for HIF-1 and von Hippel-Lindau"، J. Biol. Chem.، 278 (9): 7558–63، 2003، doi:10.1074/jbc.M210385200، PMID 12482756.
- "Catalytic properties of the asparaginyl hydroxylase (FIH) in the oxygen sensing pathway are distinct from those of its prolyl 4-hydroxylases"، J. Biol. Chem.، 279 (11): 9899–904، 2004، doi:10.1074/jbc.M312254200، PMID 14701857.
- "Substrate requirements of the oxygen-sensing asparaginyl hydroxylase factor-inhibiting hypoxia-inducible factor"، J. Biol. Chem.، 279 (14): 14391–7، 2004، doi:10.1074/jbc.M313614200، PMID 14734545.
- "Histone deacetylase 7 associates with hypoxia-inducible factor 1alpha and increases transcriptional activity"، J. Biol. Chem.، 279 (40): 41966–74، 2004، doi:10.1074/jbc.M406320200، PMID 15280364.
- "Towards a proteome-scale map of the human protein-protein interaction network"، Nature، 437 (7062): 1173–8، 2005، doi:10.1038/nature04209، PMID 16189514.
- "Posttranslational hydroxylation of ankyrin repeats in IκB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH)"، Proc. Natl. Acad. Sci. U.S.A.، 103 (40): 14767–72، 2006، doi:10.1073/pnas.0606877103، PMC 1578504، PMID 17003112.
- "Asparaginyl hydroxylation of the Notch ankyrin repeat domain by factor inhibiting hypoxia-inducible factor"، J. Biol. Chem.، 282 (33): 24027–38، 2007، doi:10.1074/jbc.M704102200، PMID 17573339.
بوابة طب
بوابة الكيمياء الحيوية
بوابة علم الأحياء الخلوي والجزيئي
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.