PDCD4
PDCD4 (Programmed cell death 4) هوَ بروتين يُشَفر بواسطة جين PDCD4 في الإنسان.[1][2][3]
الوظيفة
المراجع
- EntrezGene 27250
- "Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells"، The Journal of Biological Chemistry، 283 (2): 1026–33، 2008، doi:10.1074/jbc.M707224200، PMID 17991735.
- "Differential transcriptional regulation of CD161 and a novel gene, 197/15a, by IL-2, IL-15, and IL-12 in NK and T cells"، Journal of Immunology، 161 (7): 3493–500، 1998، PMID 9759869.
قراءة متعمقة
- "Programmed Cell Death Protein 4 (PDCD4) Acts As a Tumor Suppressor in Neuroendocrine Tumor Cells"، Annals of the New York Academy of Sciences، 1014: 220–1، 2004، doi:10.1196/annals.1294.024، PMID 15153438.
- "Oligo-capping: A simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides"، Gene، 138 (1–2): 171–4، 1994، doi:10.1016/0378-1119(94)90802-8، PMID 8125298.
- "Isolation of a novel mouse gene MA-3 that is induced upon programmed cell death"، Gene، 166 (2): 297–301، 1995، doi:10.1016/0378-1119(95)00607-9، PMID 8543179.
- "Construction and characterization of a full length-enriched and a 5′-end-enriched cDNA library"، Gene، 200 (1–2): 149–56، 1997، doi:10.1016/S0378-1119(97)00411-3، PMID 9373149.
- "Novel human PDCD4 (H731) gene expressed in proliferative cells is expressed in the small duct epithelial cells of the breast as revealed by an anti-H731 antibody"، Pathology International، 49 (12): 1067–77، 1999، doi:10.1046/j.1440-1827.1999.00995.x، PMID 10632927.
- Soejima, H.؛ Miyoshi, O.؛ Yoshinaga, H.؛ Masaki, Z.؛ Ozaki, I.؛ Kajiwara, S.؛ Niikawa, N.؛ Matsuhashi, S.؛ Mukai, T. (1999)، "Assignment1 of the programmed cell death 4 gene (PDCD4) to human chromosome band 10q24 by in situ hybridization"، Cytogenetic and Genome Research، 87: 113–4، doi:10.1159/000015408.
- "Up-regulation of PDCD4 in senescent human diploid fibroblasts"، Biochemical and Biophysical Research Communications، 293 (1): 617–21، 2002، doi:10.1016/S0006-291X(02)00264-4، PMID 12054647.
- "Loss of PDCD4 expression in human lung cancer correlates with tumour progression and prognosis"، The Journal of Pathology، 200 (5): 640–6، 2003، doi:10.1002/path.1378، PMID 12898601.
- "A Novel Function of the MA-3 Domains in Transformation and Translation Suppressor Pdcd4 is Essential for Its Binding to Eukaryotic Translation Initiation Factor 4A"، Molecular and Cellular Biology، 24 (9): 3894–906، 2004، doi:10.1128/MCB.24.9.3894-3906.2004، PMC 387765، PMID 15082783.
- "Robust Phosphoproteomic Profiling of Tyrosine Phosphorylation Sites from Human T Cells Using Immobilized Metal Affinity Chromatography and Tandem Mass Spectrometry"، Analytical Chemistry، 76 (10): 2763–72، 2004، doi:10.1021/ac035352d، PMID 15144186.
- "Programmed cell death protein 4 suppresses CDK1/cdc2 via induction of p21Waf1/Cip1"، AJP: Cell Physiology، 287 (6): C1541–6، 2004، doi:10.1152/ajpcell.00025.2004، PMID 15317660.
- "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells"، Nature Biotechnology، 23 (1): 94–101، 2004، doi:10.1038/nbt1046، PMID 15592455.
- "Towards a proteome-scale map of the human protein–protein interaction network"، Nature، 437 (7062): 1173–8، 2005، doi:10.1038/nature04209، PMID 16189514.
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: الوسيط|إظهار المؤلفين=8
غير صالح (مساعدة) - "Akt Phosphorylates and Regulates Pdcd4 Tumor Suppressor Protein"، Cancer Research، 65 (24): 11282–6، 2005، doi:10.1158/0008-5472.CAN-05-3469، PMID 16357133.
- "Tumorigenesis Suppressor Pdcd4 Down-Regulates Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1 Expression to Suppress Colon Carcinoma Cell Invasion"، Molecular and Cellular Biology، 26 (4): 1297–306، 2006، doi:10.1128/MCB.26.4.1297-1306.2006، PMC 1367180، PMID 16449643.
- بوابة الكيمياء الحيوية
- بوابة طب
- بوابة علم الأحياء الخلوي والجزيئي
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