Cloxotestosterone acetate

Cloxotestosterone acetate (INN; brand name Caprosem), also known as testosterone 17β-chloral hemiacetal O-acetate, is a synthetic, injected anabolic–androgenic steroid (AAS) and an androgen ether and ester – specifically, the O-acetate ester of cloxotestosterone, the 17β-trichloro hemiacetal ether of testosterone.[1] It is administered via intramuscular injection as a 100 mg, 2 mL aqueous suspension and lasts 4 to 6 weeks with a single administration.[2] The drug was first marketed in the early 1960s.[2]

Cloxotestosterone acetate
Clinical data
Trade namesCaprosem
Other namesTestosterone 17β-chloral hemiacetal O-acetate; 17β-(1-(Acetyloxy)-2,2,2-trichloroethoxy)androst-4-en-3-one
Routes of
administration		Intramuscular injection
Identifiers
IUPAC name
  • [2,2,2-trichloro-1-[[(8R,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]oxy]ethyl] acetate
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC23H31Cl3O4
Molar mass477.85 g·mol−1
3D model (JSmol)
SMILES
  • CC(=O)OC(C(Cl)(Cl)Cl)O[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C
InChI
  • InChI=1S/C23H31Cl3O4/c1-13(27)29-20(23(24,25)26)30-19-7-6-17-16-5-4-14-12-15(28)8-10-21(14,2)18(16)9-11-22(17,19)3/h12,16-20H,4-11H2,1-3H3/t16-,17-,18-,19-,20?,21-,22-/m0/s1
  • Key:SJWGVEPLFJGWNB-UWSXKFMVSA-N

See also

References
  1. Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 641–. ISBN 978-1-4757-2085-3.
  2. "Advertisements". Proceedings of the Royal Society of Medicine. 56 (1). 1963. PMC 1896961.


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