Fenclozic acid

Fenclozic acid is an analgesic, antipyretic, and anti-inflammatory drug.[1] It has been withdrawn in 1970 due to jaundice.[2]

Fenclozic acid
Identifiers
IUPAC name
  • [2-(4-Chlorophenyl)-1,3-thiazol-4-yl]acetic acid
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC11H8ClNO2S
Molar mass253.70 g·mol−1
3D model (JSmol)
SMILES
  • c1cc(ccc1c2nc(cs2)CC(=O)O)Cl
InChI
  • InChI=1S/C11H8ClNO2S/c12-8-3-1-7(2-4-8)11-13-9(6-16-11)5-10(14)15/h1-4,6H,5H2,(H,14,15) N
  • Key:APBSKHYXXKHJFK-UHFFFAOYSA-N N
 NY (what is this?)  (verify)

References
  1. US 3538107, Hepworth W, Stacey GJ, "Aryl-thiazolyl-acetic acid derivatives", issued 1970, assigned to Imperial Chemical Industries Ltd
  2. Fung M, Thornton A, Mybeck K, Wu JH, Hornbuckle K, Muniz E (1 January 2001). "Evaluation of the Characteristics of Safety Withdrawal of Prescription Drugs from Worldwide Pharmaceutical Markets-1960 to 1999". Therapeutic Innovation & Regulatory Science. 35 (1): 293–317. doi:10.1177/009286150103500134. S2CID 73036562.


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