Morniflumate

Morniflumate is a nonsteroidal anti-inflammatory drug (NSAID).[1][2][3]

Morniflumate
Clinical data
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
IUPAC name
  • 2-morpholin-4-ylethyl 2-{[3-(trifluoromethyl)phenyl]amino}nicotinate
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
ECHA InfoCard100.207.566
Chemical and physical data
FormulaC19H20F3N3O3
Molar mass395.382 g·mol−1
3D model (JSmol)
SMILES
  • FC(F)(F)c1cc(ccc1)Nc2ncccc2C(=O)OCCN3CCOCC3
InChI
  • InChI=1S/C19H20F3N3O3/c20-19(21,22)14-3-1-4-15(13-14)24-17-16(5-2-6-23-17)18(26)28-12-9-25-7-10-27-11-8-25/h1-6,13H,7-12H2,(H,23,24) Y
  • Key:LDXSPUSKBDTEKA-UHFFFAOYSA-N Y
  (verify)

References
  1. Melica A, Donateo L, Gerardi R, Parenti M (1991). "[A new anti-inflammatory-analgesic-antipyretic, morniflumate, in the treatment of chronic recurring bronchitis]". Rivista Europea per le Scienze Mediche e Farmacologiche = European Review for Medical and Pharmacological Sciences = Revue Européenne Pour les Sciences Médicales et Pharmacologiques. 13 (1–2): 51–60. PMID 1796197.
  2. Civelli M, Vigano T, Acerbi D, Caruso P, Giossi M, Bongrani S, Folco GC (July 1991). "Modulation of arachidonic acid metabolism by orally administered morniflumate in man". Agents and Actions. 33 (3–4): 233–9. doi:10.1007/bf01986568. PMID 1659152.
  3. Schiantarelli P, Cadel S, Acerbi D (February 1984). "A gastroprotective anti-inflammatory agent: the beta-morpholinoethyl ester of niflumic acid (morniflumate)". Agents and Actions. 14 (2): 247–56. doi:10.1007/BF01966649. PMID 6608862.


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