Guacetisal

Guacetisal is a drug that has been used to treat inflammatory respiratory diseases.[1] Chemically, it is an ester resulting from the combination of aspirin and guaiacol.

Guacetisal
Clinical data
Trade namesBroncaspin; Balsacetil; Guaiaspir; Prontomucil
Other namesAspirin guaiacol ester; O-Methoxyphenyl salicylate acetate
ATC code
Identifiers
IUPAC name
  • 2-Methoxyphenyl 2-acetoxybenzoate
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.054.221
Chemical and physical data
FormulaC16H14O5
Molar mass286.283 g·mol−1
3D model (JSmol)
Melting point72 to 74.5 °C (161.6 to 166.1 °F)
SMILES
  • O=C(Oc1ccccc1C(=O)Oc2ccccc2OC)C
InChI
  • InChI=1S/C16H14O5/c1-11(17)20-13-8-4-3-7-12(13)16(18)21-15-10-6-5-9-14(15)19-2/h3-10H,1-2H3
  • Key:HSJFYRYGGKLQBT-UHFFFAOYSA-N

References
  1. Vizioli A, Zamperini D, Ursaia G (December 1982). "[Clinical trial of guacetisal in aged subjects with inflammatory diseases of the respiratory tract]". La Clinica Terapeutica. 103 (5): 527–33. PMID 6761043.
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