Flumizole

Flumizole is an antiinflammatory agent. More specifically, it is a nonsteroidal anti-inflammatory drug (NSAID) that acts via inhibition of the enzyme cyclooxygenase (COX).[1]

Flumizole
Clinical data
ATC code
  • none
Identifiers
IUPAC name
  • 4,5-bis(4-methoxyphenyl)-2-(trifluoromethyl)-1H-imidazole
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC18H15F3N2O2
Molar mass348.325 g·mol−1
3D model (JSmol)
SMILES
  • FC(F)(F)c2[nH]c(c(c1ccc(OC)cc1)n2)c3ccc(OC)cc3
InChI
  • InChI=1S/C18H15F3N2O2/c1-24-13-7-3-11(4-8-13)15-16(23-17(22-15)18(19,20)21)12-5-9-14(25-2)10-6-12/h3-10H,1-2H3,(H,22,23)
  • Key:OPYFPDBMMYUPME-UHFFFAOYSA-N

References
  1. Wiseman EH, McIlhenny HM, Bettis JW (September 1975). "Flumizole, a new nonsteroidal anti-inflammatory agent". Journal of Pharmaceutical Sciences. 64 (9): 1469–75. doi:10.1002/jps.2600640909. PMID 810570.
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