Bekanamycin
Names | |
---|---|
IUPAC name
| |
Clinical data | |
WHO AWaRe | UnlinkedWikibase error: ⧼unlinkedwikibase-error-statements-entity-not-set⧽ |
External links | |
AHFS/Drugs.com | International Drug Names |
Legal | |
Legal status |
|
Chemical and physical data | |
Formula | C18H37N5O10 |
Molar mass | 483.519 g·mol−1 |
3D model (JSmol) | |
SMILES
| |
InChI
|
Bekanamycin (INN; kanamycin B) is an aminoglycoside antibiotic.[1][2] Per an article in Nature 2011, it was discovered that parallel pathways of kanamycin biosynthesis occurs[3] though other article(s) have indicated a different proposal.[4]
References
- ↑ Morales MA, Castrillon JL, Hernandez DA (1993). "Effects of bekanamycin and dibekacin on the electrical activity of cardiac pacemaker cells". Archives of Medical Research. 24 (4): 339–45. PMID 8118157.
- ↑ PubChem. "Bekanamycin". pubchem.ncbi.nlm.nih.gov. Archived from the original on 2023-06-03. Retrieved 2023-07-04.
- ↑ Park, Je Won; Park, Sung Ryeol; Nepal, Keshav Kumar; Han, Ah Reum; Ban, Yeon Hee; Yoo, Young Ji; Kim, Eun Ji; Kim, Eui Min; Kim, Dooil; Sohng, Jae Kyung; Yoon, Yeo Joon (9 October 2011). "Discovery of parallel pathways of kanamycin biosynthesis allows antibiotic manipulation". Nature Chemical Biology. 7 (11): 843–852. doi:10.1038/nchembio.671. ISSN 1552-4469. Archived from the original on 12 February 2023. Retrieved 23 August 2023.
- 1 2 Gao, W; Wu, Z; Sun, J; Ni, X; Xia, H (2017). "Modulation of kanamycin B and kanamycin A biosynthesis in Streptomyces kanamyceticus via metabolic engineering". PloS one. 12 (7): e0181971. doi:10.1371/journal.pone.0181971. PMID 28753625. Retrieved 23 August 2023.. These results clarified that kanamycin biosynthesis does not proceed through the parallel pathway and that synthesis of kanamycin A from kanamycin B is catalyzed by KanJ and KanK in S. kanamyceticus
External links
Identifiers: |
|
---|
This article is issued from Offline. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.