Eperezolid

Eperezolid
Clinical data
ATC code	none;
Identifiers
	IUPAC name (S)-N-[[3-[3-Fluoro-4-[4-(2-hydroxyacetyl)piperazin-; 1-yl]phenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide;
CAS Number	165800-04-4 ;
PubChem CID	73214;
ChemSpider	65969 ;
UNII	C460ZSU1OW;
KEGG	D04017 ;
ChEMBL	ChEMBL47955 ;
CompTox Dashboard (EPA)	DTXSID50168028 ;
Chemical and physical data
Formula	C18H23FN4O5
Molar mass	394.40 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC(=O)NC[C@H]1CN(C(=O)O1)C2=CC(=C(C=C2)N3CCN(CC3)C(=O)CO)F;
	InChI InChI=1S/C18H23FN4O5/c1-12(25)20-9-14-10-23(18(27)28-14)13-2-3-16(15(19)8-13)21-4-6-22(7-5-21)17(26)11-24/h2-3,8,14,24H,4-7,9-11H2,1H3,(H,20,25)/t14-/m0/s1 ; Key:SIMWTRCFFSTNMG-AWEZNQCLSA-N ;
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Eperezolid is an oxazolidinone antibiotic.

Synthesis

Eperezolid synthesis ^[1]

↑ Brickner SJ, Hutchinson DK, Barbachyn MR, Manninen PR, Ulanowicz DA, Garmon SA, et al. (February 1996). "Synthesis and antibacterial activity of U-100592 and U-100766, two oxazolidinone antibacterial agents for the potential treatment of multidrug-resistant gram-positive bacterial infections". Journal of Medicinal Chemistry. 39 (3): 673–9. doi:10.1021/jm9509556. PMID 8576909.

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