Kitasamycin

Kitasamycin
Clinical data
Other namesTurimycin
AHFS/Drugs.comInternational Drug Names
ATCvet code
Identifiers
IUPAC name
  • [(4R,5S,6S,7R,9R,10R,11E,13E,16R)-6-{[(2S,3R,4R,5S,6R)-5-{[(2S,4R,5S,6S)-4,5-Dihydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-4,10-dihydroxy-5-methoxy-9,16-dimethyl-2-oxooxacyclohexadeca-11,13-dien-7-yl]acetaldehyde (non-preferred name)
CAS Number
PubChem CID
ChemSpider
ChEMBL
Chemical and physical data
FormulaC35H59NO13
Molar mass701.851 g·mol−1
3D model (JSmol)
SMILES
  • C[C@@H]1C/C=C/C=C/[C@@H]([C@@H](C[C@@H]([C@@H]([C@H]([C@@H](CC(=O)O1)O)OC)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)C)O[C@H]3C[C@@]([C@H]([C@@H](O3)C)O)(C)O)N(C)C)O)CC=O)C)O
InChI
  • InChI=1S/C35H59NO13/c1-19-16-23(14-15-37)31(32(44-8)25(39)17-26(40)45-20(2)12-10-9-11-13-24(19)38)49-34-29(41)28(36(6)7)30(21(3)47-34)48-27-18-35(5,43)33(42)22(4)46-27/h9-11,13,15,19-25,27-34,38-39,41-43H,12,14,16-18H2,1-8H3/b10-9+,13-11+/t19-,20-,21-,22+,23+,24+,25-,27+,28-,29-,30-,31+,32+,33+,34+,35-/m1/s1 ☒N
  • Key:XYJOGTQLTFNMQG-KJHBSLKPSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Kitasamycin (INN) is a macrolide antibiotic. It is produced by Streptomyces kitasatoensis.[1] The drug has antimicrobial activity against a wide spectrum of pathogens. There are several generic names of this drug such as:[2]

  • Kitasamycin (OS: BAN, JAN, USAN)
  • Kitasamycine (OS: DCF)
  • C 637 (IS)
  • Katasamycin (IS)
  • Leucomycin (IS)
  • Kitasamycin (PH: JP XV)
  • Kitasamycin Acetate (OS: JAN)
  • Leucomycin Acetate (IS)
  • Kitasamycin Acetate (PH: JP XV)
  • Kitasamycin Tartrate (OS: JAN)
  • Leucomycin Tartrate (IS)
  • Kitasamycin Tartrate (PH: JP XV)

References

  1. Zheng Q, Gao S (November 2016). "The effect of surfactant on fermentation of kitasamycin in Streptomyces kitasatoensis". Biotechnology and Applied Biochemistry. 63 (6): 895–900. doi:10.1002/bab.1443. PMID 26339801.
  2. "Kitasamycin". Drugs.com. Archived from the original on 20 October 2012.


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