Miocamycin

Miocamycin
Clinical data
AHFS/Drugs.com	International Drug Names
ATC code	J01FA11 (WHO) ;
Identifiers
	IUPAC name (2S,3S,4R,6S)-6-{[(2R,3S,4R,5R,6S)-6-{[(4S,5R,6S,7R,9R,10R,11E,13E,16R)-10-(acetyloxy)-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)-4-propoxy-1-oxacyclohexadeca-11,13-dien-6-yl]oxy}-4-(dimethylamino)-5-hydroxy-2-methyloxan-3-yl]oxy}-2,4-dimethyl-3-propoxyoxan-4-yl acetate;
CAS Number	55881-07-7;
PubChem CID	6475694;
ChemSpider	16735908 ;
UNII	3T48CPS7U2;
ChEMBL	ChEMBL1091024 ;
CompTox Dashboard (EPA)	DTXSID60905087 ;
ECHA InfoCard	100.054.418
Chemical and physical data
Formula	C45H75NO15
Molar mass	870.087 g·mol−1
3D model (JSmol)	Interactive image;
Melting point	220 °C (428 °F)
Solubility in water	Slightly soluble in water; Soluble in methanol, acetone and chloroform. mg/mL (20 °C)
	SMILES CC(=O)O[C@H]3/C=C/C=C/C[C@@H](C)OC(=O)C[C@@H](OC(=O)CC)[C@H](OC)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O[C@H]1C[C@@](C)(OC(C)=O)[C@@H](OC(=O)CC)[C@H](C)O1)[C@H](N(C)C)[C@H]2O)[C@@H](CC=O)C[C@H]3C;
	InChI InChI=1S/C45H71NO17/c1-13-34(50)59-33-23-36(52)55-26(4)18-16-15-17-19-32(58-29(7)48)25(3)22-31(20-21-47)41(42(33)54-12)62-44-39(53)38(46(10)11)40(27(5)57-44)61-37-24-45(9,63-30(8)49)43(28(6)56-37)60-35(51)14-2/h15-17,19,21,25-28,31-33,37-44,53H,13-14,18,20,22-24H2,1-12H3/b16-15+,19-17+/t25-,26-,27-,28+,31+,32+,33-,37+,38-,39-,40-,41+,42+,43+,44+,45-/m1/s1 ; Key:GQNZGCARKRHPOH-RQIKCTSVSA-N ;
	(verify)

Miocamycin is a macrolide antibiotic.^[1]

References

↑ Holliday SM, Faulds D (October 1993). "Miocamycin. A review of its antimicrobial activity, pharmacokinetic properties and therapeutic potential". Drugs. 46 (4): 720–45. doi:10.2165/00003495-199346040-00008. PMID 7506653.

This article is issued from Offline. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.