HHCP-O-acetate

HHCP-O-acetate (HHCPO, HHCP-O) is a semi-synthetic derivative of tetrahydrocannabiphorol (THCP) derived in several steps by hydrogenation to hexahydrocannabiphorol (HHCP) followed by acetylation of the OH group. It has been found as a component of grey-market cannabis products such as e-cigarette liquids and edible gummy lollies, and is allegedly a potent and long-lasting psychoactive cannabinoid.[1]

HHCP-O-acetate
Identifiers
  • (6aR,10aR)-6,6,9-trimethyl-3-heptyl-6a,7,8,9,10,10a-hexahydrobenzo[c]chromen-1-yl acetate
Chemical and physical data
FormulaC25H38O3
Molar mass386.576 g·mol−1
3D model (JSmol)
  • CC(=O)Oc1cc(CCCCCCC)cc2OC(C)(C)[C@@H]3CCC(C)C[C@H]3c21

Confusion about acronym

Some vendors have mistakenly claimed that HHCPO stands for hexahydrocannabinol propionate (HHC-P) or hexahydrocannabinol cyclopropyl ether, but these are different compounds.

Hexahydrocannabinol propionate (left) and Hexahydrocannabinol cyclopropyl ether (right)

See also

References
  1. Erickson BE (2023). "Waiting for CBD regulations in the US". Chemical & Engineering News. 101 (28): 17–19. doi:10.1021/cen-10128-feature1. S2CID 261318144.
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