Nesvacumab
| Monoclonal antibody | |
|---|---|
| Type | Whole antibody |
| Source | Human |
| Target | Angiopoietin 2 |
| Clinical data | |
| ATC code |
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| Legal status | |
| Legal status |
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| Identifiers | |
| CAS Number | |
| IUPHAR/BPS | |
| ChemSpider |
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| Chemical and physical data | |
| Formula | C6440H9966N1722O2008S38 |
| Molar mass | 144860.89 g·mol−1 |
Nesvacumab is an experimental monoclonal antibody originally designed for the treatment of cancer. It targets the protein angiopoietin 2.[1] As of May 2017, it is in Phase II clinical trials for the treatment of diabetic macular edema.[2][3]
This drug is being developed by Regeneron Pharmaceuticals.
References
- ↑ Statement On A Nonproprietary Name Adopted By The USAN Council - Nesvacumab, American Medical Association.
- ↑ Clinical trial number NCT02713204 for "Anti-angiOpoeitin 2 Plus Anti-vascular eNdothelial Growth Factor as a therapY for Neovascular Age Related Macular Degeneration: Evaluation of a fiXed Combination Intravitreal Injection (ONYX)" at ClinicalTrials.gov
- ↑ Clinical trial number NCT02712008 for "Anti-vasculaR Endothelial Growth Factor plUs Anti-angiopoietin 2 in Fixed comBination therapY: Evaluation for the Treatment of Diabetic Macular Edema (RUBY)" at ClinicalTrials.gov
Monoclonals for bone, musculoskeletal, circulatory, and neurologic systems | |||||||||
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| Bone |
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| Musculoskeletal |
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| Circulatory |
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| Neurologic |
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| Angiogenesis inhibitor |
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| Growth factor |
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Growth factor receptor modulators | |||||||||||
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| Angiopoietin |
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| CNTF |
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| EGF (ErbB) |
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| FGF |
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| HGF (c-Met) |
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| IGF |
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| LNGF (p75NTR) |
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| PDGF |
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| RET (GFL) |
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| SCF (c-Kit) | |||||||||||
| TGFβ |
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| Trk |
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| VEGF |
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| Others |
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