Metethoheptazine

Metethoheptazine[1] (WY-535) is an opioid analgesic from the phenazepine family. It was invented in the 1960s.[2]

Metethoheptazine
Clinical data
Other namesWY-535
ATC code
  • none
Identifiers
IUPAC name
  • ethyl 1,3-dimethyl-4-phenylazepane-4-carboxylate
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC17H25NO2
Molar mass275.392 g·mol−1
3D model (JSmol)
SMILES
  • O=C(OCC)C2(c1ccccc1)CCCN(C)CC2C
InChI
  • InChI=1S/C17H25NO2/c1-4-20-16(19)17(15-9-6-5-7-10-15)11-8-12-18(3)13-14(17)2/h5-7,9-10,14H,4,8,11-13H2,1-3H3 Y
  • Key:BOSULDNQDJLKKL-UHFFFAOYSA-N Y
 NY (what is this?)  (verify)

Metethoheptazine produces similar effects to other opioids, including analgesia, sedation, dizziness and nausea.

Metethoheptazine is not listed as a controlled substance under the Controlled Substances Act 1970 in the United States.[3] The Canadian Controlled Drugs and Substances Act specifically excludes the phenazepine opioids from control.

References
  1. GB 843924, "Substituted azacycloheptanes", assigned to American Home Products
  2. Walkenstein SS, Corradino RA, Wiser R, Gudmundsen CH (February 1965). "Metabolism of the Non-Narcotic Analgesic, WY-5355". Biochemical Pharmacology. 14 (2): 121–8. doi:10.1016/0006-2952(65)90067-5. PMID 14332457.
  3. "Conversion Factors for Controlled Substances". Diversion Control Division. Drug Enforcement Administration, U.S. Department of Justice. Retrieved 8 October 2018.


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