RAM-378

RAM-378[1](7,8-Dihydro-14-hydroxy-N-phenethylnormorphine) is an opioid analgesic. It is the N-phenethyl derivative of hydromorphinol.

RAM-378
Identifiers
IUPAC name
  • 3,6,14-trihydroxy-4,5α-epoxy-17-(2-phenylethyl)morphinan
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC24H27NO4
Molar mass393.483 g·mol−1
3D model (JSmol)
SMILES
  • C1C[C@]2([C@H]3CC4=C5[C@@]2(CCN3CCC6=CC=CC=C6)[C@H]([C@H]1O)OC5=C(C=C4)O)O
InChI
  • InChI=1S/C24H27NO4/c26-17-7-6-16-14-19-24(28)10-8-18(27)22-23(24,20(16)21(17)29-22)11-13-25(19)12-9-15-4-2-1-3-5-15/h1-7,18-19,22,26-28H,8-14H2/t18-,19+,22-,23-,24+/m0/s1
  • Key:GAHRZWMAHDWVCL-VKJMTUIMSA-N
  (verify)

See also

References
  1. Ben Haddou T, Béni S, Hosztafi S, Malfacini D, Calo G, Schmidhammer H, Spetea M (2014). "Pharmacological investigations of N-substituent variation in morphine and oxymorphone: opioid receptor binding, signaling and antinociceptive activity". PLOS ONE. 9 (6): e99231. Bibcode:2014PLoSO...999231B. doi:10.1371/journal.pone.0099231. PMC 4053365. PMID 24919067.


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.