Cefozopran

Cefozopran
Clinical data
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
IUPAC name
  • (6R,7R)-7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)- 2-methoxyiminoacetyl]amino]-3-(imidazo[2,3-f]pyridazin- 4-ium-1-ylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0] oct-2-ene-2-carboxylate
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
ECHA InfoCard100.107.680
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Chemical and physical data
FormulaC19H17N9O5S2
Molar mass515.52 g·mol−1
3D model (JSmol)
SMILES
  • O=C2N1/C(=C(\CS[C@@H]1[C@@H]2NC(=O)C(=N\OC)/c3nc(sn3)N)Cn5c4cccn[n+]4cc5)C([O-])=O
InChI
  • InChI=1S/C19H17N9O5S2/c1-33-24-11(14-23-19(20)35-25-14)15(29)22-12-16(30)28-13(18(31)32)9(8-34-17(12)28)7-26-5-6-27-10(26)3-2-4-21-27/h2-6,12,17H,7-8H2,1H3,(H3-,20,22,23,25,29,31,32)/b24-11-/t12-,17-/m1/s1 ☒N
  • Key:QDUIJCOKQCCXQY-WHJQOFBOSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Cefozopran (INN) is a fourth-generation cephalosporin.[1]

Spectrum of bacterial susceptibility and resistance

Most of the strains of Stenotrophomonas maltophilia have developed resistance toward cefozopran.[2]

References

  1. ↑ Chang XM (December 1996). "Chapter 34: Market to Market". In Bristol JA (ed.). Annual Reports in Medicinal Chemistry. Vol. 31. San Diego, Calif.: Academic Press. p. 339. ISBN 978-0-08-058375-4.
  2. ↑ "Cefozopran Susceptibility and Resistance Data" (PDF). Retrieved 23 July 2013.


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