Extended-spectrum penicillin

The extended-spectrum penicillins are a group of antibiotics that have the widest antibacterial spectrum of all penicillins.[1] Some sources identify them with antipseudomonal penicillins,[2] others consider these types to be distinct.[3] This group includes the carboxypenicillins and the ureidopenicillins. Aminopenicillins, in contrast, do not have activity against Pseudomonas species, as their positively charged amino group does not hinder degradation by bacterially produced beta-lactamases.[4]

Products

See also

References

  1. ↑ Comprehensive Pharmacy Review, Leon Shargel, 6th edition, p917
  2. ↑ Kester, Mark; Karpa, Kelly Dowhower; Vrana, Kent E. (2011). Elsevier's Integrated Review Pharmacology E-Book. Elsevier Health Sciences. ISBN 9781455727032.
  3. ↑ Clark, Michelle A.; Harvey, Richard A.; Finkel, Richard; Rey, Jose A.; Whalen, Karen, eds. (2011). Pharmacology. Lippincott Williams & Wilkins. p. 383. ISBN 9781451113143.
  4. ↑ Golan, David E. (15 December 2011). Principles of Pharmacology (2 ed.). Lippincott Williams & Wilkins. p. 610. ISBN 978-1608312702.
This article is issued from Offline. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.