PYCARD
PYCARD (PYD and CARD domain containing) هوَ بروتين يُشَفر بواسطة جين PYCARD في الإنسان.[1][2][3]
المراجع
- Alba, Eva de (20 نوفمبر 2009)، "Structure and Interdomain Dynamics of Apoptosis-associated Speck-like Protein Containing a CARD (ASC)"، Journal of Biological Chemistry (باللغة الإنجليزية)، 284 (47): 32932–32941، doi:10.1074/jbc.M109.024273، ISSN 0021-9258، PMC 2781708، PMID 19759015، مؤرشف من الأصل في 03 يونيو 2018.
- "Entrez Gene: PYCARD PYD and CARD domain containing"، مؤرشف من الأصل في 05 ديسمبر 2010، اطلع عليه بتاريخ 18 سبتمبر 2010.
- Dunn, JH؛ Fujita, M (2015)، "PYCARD (PYD and CARD domain containing)"، Atlas of Genetics and Cytogenetics in Oncology and Haematology (باللغة الإنجليزية) (4)، doi:10.4267/2042/56440، ISSN 1768-3262، مؤرشف من الأصل في 07 ديسمبر 2019.
قراءة متعمقة
- "ASC, a novel 22-kDa protein, aggregates during apoptosis of human promyelocytic leukemia HL-60 cells"، J. Biol. Chem.، 274 (48): 33835–8، 1999، doi:10.1074/jbc.274.48.33835، PMID 10567338.
- "Activating protein-1, nuclear factor-kappaB, and serum response factor as novel target molecules of the cancer-amplified transcription coactivator ASC-2"، Mol. Endocrinol.، 14 (6): 915–25، 2000، doi:10.1210/mend.14.6.0471، PMID 10847592.
- "TMS1, a novel proapoptotic caspase recruitment domain protein, is a target of methylation-induced gene silencing in human breast cancers"، Cancer Res.، 60 (22): 6236–42، 2000، PMID 11103776.
- "Activation of a caspase-9-mediated apoptotic pathway by subcellular redistribution of the novel caspase recruitment domain protein TMS1"، Cancer Res.، 60 (22): 6243–7، 2000، PMID 11103777.
- "The pyrin domain: a possible member of the death domain-fold family implicated in apoptosis and inflammation"، Curr. Biol.، 11 (4): R118-20، 2001، doi:10.1016/S0960-9822(01)00056-2، PMID 11250163.
- "Human CARD12 is a novel CED4/Apaf-1 family member that induces apoptosis"، Biochem. Biophys. Res. Commun.، 284 (1): 77–82، 2001، doi:10.1006/bbrc.2001.4928، PMID 11374873.
- "Interaction between pyrin and the apoptotic speck protein (ASC) modulates ASC-induced apoptosis"، J. Biol. Chem.، 276 (42): 39320–9، 2001، doi:10.1074/jbc.M104730200، PMID 11498534.
- "Methylation-mediated silencing of TMS1/ASC is accompanied by histone hypoacetylation and CpG island-localized changes in chromatin architecture"، J. Biol. Chem.، 277 (7): 4951–8، 2002، doi:10.1074/jbc.M109809200، PMID 11733524.
- "PYPAF1, a PYRIN-containing Apaf1-like protein that assembles with ASC and regulates activation of NF-kappa B"، J. Biol. Chem.، 277 (13): 11570–5، 2002، doi:10.1074/jbc.M112208200، PMID 11786556.
- "The PYRIN-CARD protein ASC is an activating adaptor for caspase-1"، J. Biol. Chem.، 277 (24): 21119–22، 2002، doi:10.1074/jbc.C200179200، PMID 11967258.
- "PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing"، J. Biol. Chem.، 277 (33): 29874–80، 2002، doi:10.1074/jbc.M203915200، PMID 12019269.
- "ASC, which is composed of a PYD and a CARD, is up-regulated by inflammation and apoptosis in human neutrophils"، Biochem. Biophys. Res. Commun.، 293 (5): 1314–8، 2002، doi:10.1016/S0006-291X(02)00384-4، PMID 12054656.
- "The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta"، Mol. Cell، 10 (2): 417–26، 2002، doi:10.1016/S1097-2765(02)00599-3، PMID 12191486.
- "The PAAD/PYRIN-family protein ASC is a dual regulator of a conserved step in nuclear factor kappaB activation pathways"، J. Exp. Med.، 196 (12): 1605–15، 2002، doi:10.1084/jem.20021552، PMC 2196065، PMID 12486103.
- "A proapoptotic caspase recruitment domain protein gene, TMS1, is hypermethylated in human breast and gastric cancers"، Anticancer Res.، 22 (6C): 4163–8، 2003، PMID 12553049.
- "Regulation of cryopyrin/Pypaf1 signaling by pyrin, the familial Mediterranean fever gene product"، Biochem. Biophys. Res. Commun.، 302 (3): 575–80، 2003، doi:10.1016/S0006-291X(03)00221-3، PMID 12615073.
- "ASC is an activating adaptor for NF-kappa B and caspase-8-dependent apoptosis"، Biochem. Biophys. Res. Commun.، 303 (1): 69–73، 2003، doi:10.1016/S0006-291X(03)00309-7، PMID 12646168.
- "The PAAD/PYRIN-only protein POP1/ASC2 is a modulator of ASC-mediated nuclear-factor-kappa B and pro-caspase-1 regulation"، Biochem. J.، 373 (Pt 1): 101–13، 2003، doi:10.1042/BJ20030304، PMC 1223462، PMID 12656673.
- "Effects of methylation on expression of TMS1/ASC in human breast cancer cells"، Oncogene، 22 (22): 3475–88، 2003، doi:10.1038/sj.onc.1206430، PMID 12776200.
- بوابة الكيمياء الحيوية
- بوابة طب
- بوابة علم الأحياء الخلوي والجزيئي
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