RRAD
RRAD (RRAD, Ras related glycolysis inhibitor and calcium channel regulator) هوَ بروتين يُشَفر بواسطة جين RRAD في الإنسان.[1][2]
المراجع
- "Entrez Gene: RRAD Ras-related associated with diabetes"، مؤرشف من الأصل في 05 ديسمبر 2010.
- "Trinucleotide repeats at the rad locus. Allele distributions in NIDDM and mapping to a 3-cM region on chromosome 16q"، Diabetes، 44 (2): 243–7، مارس 1995، doi:10.2337/diabetes.44.2.243، PMID 7859947.
قراءة متعمقة
- "Characterization of Rad, a new member of Ras/GTPase superfamily, and its regulation by a unique GTPase-activating protein (GAP)-like activity"، J. Biol. Chem.، 270 (9): 4805–12، 1995، doi:10.1074/jbc.270.9.4805، PMID 7876254.
- "Rad: a member of the Ras family overexpressed in muscle of type II diabetic humans"، Science، 262 (5138): 1441–4، 1993، doi:10.1126/science.8248782، PMID 8248782.
- "Rad, a novel Ras-related GTPase, interacts with skeletal muscle beta-tropomyosin"، J. Biol. Chem.، 271 (2): 768–73، 1996، doi:10.1074/jbc.271.2.768، PMID 8557685.
- "Molecular cloning of the human rad gene: gene structure and complete nucleotide sequence"، Biochim. Biophys. Acta، 1316 (3): 145–8، 1996، doi:10.1016/0925-4439(96)00034-8، PMID 8781531.
- "Overexpression of Rad inhibits glucose uptake in cultured muscle and fat cells"، J. Biol. Chem.، 271 (38): 23111–6، 1996، doi:10.1074/jbc.271.38.23111، PMID 8798502.
- "Rad and Rad-related GTPases interact with calmodulin and calmodulin-dependent protein kinase II"، J. Biol. Chem.، 272 (18): 11832–9، 1997، doi:10.1074/jbc.272.18.11832، PMID 9115241.
- "Effects of phosphorylation on function of the Rad GTPase"، Biochem. J.، 333 ( Pt 3) (3): 609–14، 1998، PMC 1219623، PMID 9677319.
- "Phosphorylation-dependent association of the Ras-related GTP-binding protein Rem with 14-3-3 proteins"، Arch. Biochem. Biophys.، 368 (2): 401–12، 1999، doi:10.1006/abbi.1999.1316، PMID 10441394.
- "Interaction of the Ras-related protein associated with diabetes rad and the putative tumor metastasis suppressor NM23 provides a novel mechanism of GTPase regulation"، Proc. Natl. Acad. Sci. U.S.A.، 96 (26): 14911–8، 1999، doi:10.1073/pnas.96.26.14911، PMC 24747، PMID 10611312.
- "Regulation of growth and tumorigenicity of breast cancer cells by the low molecular weight GTPase Rad and nm23"، Cancer Res.، 61 (5): 2071–9، 2001، PMID 11280768.
- "Expression, purification, crystallization and preliminary crystallographic analysis of human Rad GTPase"، Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun.، 61 (Pt 11): 978–80، 2005، doi:10.1107/S1744309105031982، PMC 1978125، PMID 16511212.
- "Crystal structure of human Rad GTPase of the RGK-family"، Genes Cells، 11 (8): 961–8، 2006، doi:10.1111/j.1365-2443.2006.00994.x، PMID 16866878.
- "Methylation and gene silencing of the Ras-related GTPase gene in lung and breast cancers"، Ann. Surg. Oncol.، 14 (4): 1397–404، 2007، doi:10.1245/s10434-006-9089-6، PMID 17195088.
- "Dominant negative suppression of Rad leads to QT prolongation and causes ventricular arrhythmias via modulation of L-type Ca2+ channels in the heart"، Circ. Res.، 101 (1): 69–77، 2007، doi:10.1161/CIRCRESAHA.106.146399، PMID 17525370.
- "Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns"، Genome Biol.، 8 (8): R154، 2007، doi:10.1186/gb-2007-8-8-r154، PMC 2374985، PMID 17672918.
بوابة علم الأحياء الخلوي والجزيئي
بوابة طب
بوابة الكيمياء الحيوية
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.