Estradiol cypionate/hydroxyprogesterone caproate

Estradiol cypionate/hydroxyprogesterone caproate (EC/OHPC), sold under the brand name Sinbios, is a combination medication of estradiol cypionate (EC), an estrogen, and hydroxyprogesterone caproate (OHPC), a progestin, which was reportedly used as a combined injectable contraceptive in women in the early 1970s.[1] It contained 5 mg EC and 250 mg OHPC in oil solution, was provided in the form of 1 mL ampoules, and was administered by intramuscular injection at regular intervals.[1] The medication was manufactured by the pharmaceutical company Mavi in Mexico.[1]

Estradiol cypionate /
hydroxyprogesterone caproate
Estradiol cypionate (top) and
hydroxyprogesterone caproate (bottom)
Combination of
Estradiol cypionateEstrogen
Hydroxyprogesterone caproateProgestogen
Clinical data
Trade namesSinbios
Other namesEC/OHPC
Routes of
administration		Intramuscular injection

See also

References
  1. Rudel HW, Kinel FA (September 1972). "Oral Contraceptives. Human Fertility Studies and Side Effects". In Tausk M (ed.). Pharmacology of the Endocrine System and Related Drugs: Progesterone, Progestational Drugs and Antifertility Agents. Vol. II. Pergamon Press. pp. 385–469. ISBN 978-0080168128. OCLC 278011135.



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