Clomifenoxide

Clomifenoxide
Clinical data
Other namesClomifene N-oxide
Identifiers
IUPAC name
  • (E,Z)-2-(p-(2-Chloro-1,2-diphenylvinyl)phenoxy)triethylamine N-oxide
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC26H28ClNO2
Molar mass421.97 g·mol−1
3D model (JSmol)
SMILES
  • [N+](CCOc1ccc(cc1)C(=C(/c1ccccc1)Cl)\c1ccccc1)(CC)(CC)[O-]
InChI
  • InChI=1S/C26H28ClNO2/c1-3-28(29,4-2)19-20-30-24-17-15-22(16-18-24)25(21-11-7-5-8-12-21)26(27)23-13-9-6-10-14-23/h5-18H,3-4,19-20H2,1-2H3/b26-25-
  • Key:PGHWCZITRQNIPM-QPLCGJKRSA-N

Clomifenoxide (INN), also known as clomifene N-oxide, is a nonsteroidal selective estrogen receptor modulator (SERM) of the triphenylethylene group that is described as an antiestrogen and "gonad stimulant" and was never marketed.[1][2] It is an active metabolite of clomifene.[3][4]

See also

References

  1. ↑ Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 298–. ISBN 978-1-4757-2085-3.
  2. ↑ Negwer M, Scharnow HG (2001). Organic-chemical drugs and their synonyms: (an international survey). Wiley-VCH. p. 3506. ISBN 978-3-527-30247-5.
  3. ↑ Analytical Profiles of Drug Substances and Excipients. Academic Press. 20 March 1998. pp. 113–. ISBN 978-0-08-086120-3.
  4. ↑ Goodwin BL (10 November 2004). Handbook of Biotransformations of Aromatic Compounds. CRC Press. pp. 3–. ISBN 978-0-203-64196-5.



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