60S ribosomal protein L18a

60S ribosomal protein L18a is a protein that in humans is encoded by the RPL18A gene.[5][6]

RPL18A
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesRPL18A, L18A, ribosomal protein L18a
External IDsOMIM: 604178 MGI: 1924058 HomoloGene: 68104 GeneCards: RPL18A
Orthologs
SpeciesHumanMouse
Entrez

6142

76808

Ensembl

ENSG00000105640

ENSMUSG00000045128

UniProt

Q02543

P62717

RefSeq (mRNA)

NM_000980

NM_029751

RefSeq (protein)

NP_000971

NP_084027

Location (UCSC)Chr 19: 17.86 – 17.86 MbChr 8: 71.35 – 71.35 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L18AE family of ribosomal proteins. It is located in the cytoplasm. This gene is co-transcribed with the U68 snoRNA, which is located in its third intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.[6]

References

  1. GRCh38: Ensembl release 89: ENSG00000105640 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000045128 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Kenmochi N, Kawaguchi T, Rozen S, Davis E, Goodman N, Hudson TJ, Tanaka T, Page DC (Aug 1998). "A map of 75 human ribosomal protein genes". Genome Res. 8 (5): 509–23. doi:10.1101/gr.8.5.509. PMID 9582194.
  6. "Entrez Gene: RPL18A ribosomal protein L18a".

Further reading


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