60S ribosomal protein L29

60S ribosomal protein L29 is a protein that in humans is encoded by the RPL29 gene.[3][4]

RPL29
Available structures
PDBHuman UniProt search: PDBe RCSB
Identifiers
AliasesRPL29, HIP, HUML29, RPL29P10, RPL29_3_370, ribosomal protein L29
External IDsOMIM: 601832 HomoloGene: 133570 GeneCards: RPL29
Orthologs
SpeciesHumanMouse
Entrez

6159

n/a

Ensembl

ENSG00000162244

n/a

UniProt

P47914

n/a

RefSeq (mRNA)

NM_000992

n/a

RefSeq (protein)

NP_000983

n/a

Location (UCSC)Chr 3: 51.99 – 52 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Function

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 60S subunit. The protein belongs to the L29E family of ribosomal proteins. The protein is also a peripheral membrane protein expressed on the cell surface that directly binds heparin. Although this gene was previously reported to map to 3q29-qter, it is believed that it is located at 3p21.3-p21.2. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.[4]

Interactions

RPL29 has been shown to interact with BLMH.[5]

References

  1. GRCh38: Ensembl release 89: ENSG00000162244 - Ensembl, May 2017
  2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. Law PT, Tsui SK, Lam WY, Luk SC, Hwang DM, Liew CC, Lee CY, Fung KP, Waye MM (Apr 1996). "A novel cDNA encoding a human homologue of ribosomal protein L29". Biochim Biophys Acta. 1305 (3): 105–8. doi:10.1016/0167-4781(95)00224-3. PMID 8597591.
  4. "Entrez Gene: RPL29 ribosomal protein L29".
  5. Koldamova RP, Lefterov IM, DiSabella MT, Almonte C, Watkins SC, Lazo JS (Jun 1999). "Human bleomycin hydrolase binds ribosomal proteins". Biochemistry. 38 (22): 7111–7. doi:10.1021/bi990135l. PMID 10353821.

Further reading

  • Overview of all the structural information available in the PDB for UniProt: P47914 (60S ribosomal protein L29) at the PDBe-KB.


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