GPR142

GPR142
Identifiers
Aliases	GPR142, PGR2, G protein-coupled receptor 142, GPRg1b
External IDs	OMIM: 609046 MGI: 2668437 HomoloGene: 18770 GeneCards: GPR142
Gene location (Human)
Chr.	Chromosome 17 (human)[1]
End	74,372,600 bp[1]
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)[2]
End	114,697,571 bp[2]
RNA expression pattern
	Top expressed in
	islet of Langerhans; ; spleen; ; duodenum; ; lymph node; ; gastric mucosa; ; left uterine tube; ; right lobe of thyroid gland; ; appendix; ; canal of the cervix; ; fundus;
	Top expressed in
	islet of Langerhans; ; cochlea; ; pharynx; ; neck; ; habenula; ; peripheral nervous system; ; medial habenular nucleus; ; trigeminal ganglion; ; dentate gyrus; ; hypothalamus;
	More reference expression data
	n/a
Gene ontology
Molecular function	G protein-coupled receptor activity; signal transducer activity;
Cellular component	integral component of membrane; cell junction; membrane; plasma membrane; cytosol;
Biological process	G protein-coupled receptor signaling pathway; signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	350383
	217302
	ENSG00000257008
	ENSMUSG00000034677
	Q7Z601
	Q7TQN9
	NM_181790; NM_001331076; NM_001331077
	NM_181749; NM_001346772; NM_001379097
	NP_001318005; NP_001318006; NP_861455
	NP_001333701; NP_861414; NP_001366026
	Wikidata
View/Edit Human	View/Edit Mouse

Probable G-protein coupled receptor 142 is a protein that in humans is encoded by the GPR142 gene.[5][6]

GPR142 is a member of the rhodopsin family of G protein-coupled receptors (GPRs) (Fredriksson et al., 2003).[supplied by OMIM][6]

References

GRCh38: Ensembl release 89: ENSG00000257008 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000034677 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Fredriksson R, Hoglund PJ, Gloriam DE, Lagerstrom MC, Schioth HB (Nov 2003). "Seven evolutionarily conserved human rhodopsin G protein-coupled receptors lacking close relatives". FEBS Lett. 554 (3): 381–8. doi:10.1016/S0014-5793(03)01196-7. PMID 14623098. S2CID 11563502.
"Entrez Gene: GPR142 G protein-coupled receptor 142".

Vassilatis DK, Hohmann JG, Zeng H, et al. (2003). "The G protein-coupled receptor repertoires of human and mouse". Proc. Natl. Acad. Sci. U.S.A. 100 (8): 4903–8. Bibcode:2003PNAS..100.4903V. doi:10.1073/pnas.0230374100. PMC 153653. PMID 12679517.
Matsuo A, Matsumoto S, Nagano M, et al. (2005). "Molecular cloning and characterization of a novel Gq-coupled orphan receptor GPRg1 exclusively expressed in the central nervous system". Biochem. Biophys. Res. Commun. 331 (1): 363–9. doi:10.1016/j.bbrc.2005.03.174. PMID 15845401.

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