LPAR4

Lysophosphatidic acid receptor 4 also known as LPA4 is a protein that in humans is encoded by the LPAR4 gene.[5][6][7] LPA4 is a G protein-coupled receptor that binds the lipid signaling molecule lysophosphatidic acid (LPA).[8]

LPAR4
Identifiers
AliasesLPAR4, GPR23, LPA4, P2RY9, P2Y5-LIKE, P2Y9, lysophosphatidic acid receptor 4
External IDsOMIM: 300086 MGI: 1925384 HomoloGene: 3871 GeneCards: LPAR4
Orthologs
SpeciesHumanMouse
Entrez

2846

78134

Ensembl

ENSG00000147145

ENSMUSG00000049929

UniProt

Q99677

Q8BLG2

RefSeq (mRNA)

NM_001278000
NM_005296

NM_175271

RefSeq (protein)

NP_001264929
NP_005287

NP_780480

Location (UCSC)Chr X: 78.75 – 78.76 MbChr X: 105.96 – 105.98 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

See also

References

  1. GRCh38: Ensembl release 89: ENSG00000147145 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000049929 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: GPR23 G protein-coupled receptor 23".
  6. Janssens R, Boeynaems JM, Godart M, Communi D (July 1997). "Cloning of a human heptahelical receptor closely related to the P2Y5 receptor". Biochem. Biophys. Res. Commun. 236 (1): 106–12. doi:10.1006/bbrc.1997.6895. PMID 9223435.
  7. O'Dowd BF, Nguyen T, Jung BP, Marchese A, Cheng R, Heng HH, Kolakowski LF, Lynch KR, George SR (March 1997). "Cloning and chromosomal mapping of four putative novel human G-protein-coupled receptor genes". Gene. 187 (1): 75–81. doi:10.1016/S0378-1119(96)00722-6. PMID 9073069.
  8. Choi JW, Herr DR, Noguchi K, Yung YC, Lee CW, Mutoh T, Lin ME, Teo ST, Park KE, Mosley AN, Chun J (January 2010). "LPA Receptors: Subtypes and Biological Actions". Annual Review of Pharmacology and Toxicology. 50 (1): 157–186. doi:10.1146/annurev.pharmtox.010909.105753. PMID 20055701.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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